Boxed Warnings

Abacavir / Dolutegravir / Lamivudine [Triumeq]: Abacavir / Dolutegravir / Lamivudine [Triumeq] Warnings: hypersensitivity reactions, hematologic toxicity, myopathy, lactic acidosis and severe hepatomegaly, and exacerbations of hepatitis b
Abacavir / Lamivudine / Zidovudine [Trizivir]: Abacavir / Lamivudine / Zidovudine [Trizivir] Warnings: hypersensitivity reactions, hematologic toxicity, myopathy, lactic acidosis and severe hepatomegaly with steatosis, and exacerbations of hepatitis b
Abacavir / Lamivudine [Epzicom]: Abacavir / Lamivudine [Epzicom] Warnings: hypersensitivity reactions, lactic acidosis and severe hepatomegalywith steatosis, and exacerbations of hepatitis b
Abacavir Sulfate [Ziagen]: Abacavir Sulfate [Ziagen] Warnings: hypersensitivity reactions, and lactic acidosis, and severe hepatomegaly
Abaloparatide [Tymlos]: Abaloparatide [Tymlos] Warnings: risk of osteosarcoma
Abarelix [Plenaxis]: Abarelix [Plenaxis] Warnings: immediate-onset systemic allergic reactions, some resulting in hypotension and syncope, have occurred after administration.
Aceon [perindopril erbumine]: Aceon [perindopril erbumine] Warnings: fetal toxicity
Acetaminophen / Butalbital / Caffeine / Codeine [Fioricet With Codeine]: Acetaminophen / Butalbital / Caffeine / Codeine [Fioricet With Codeine] Warnings: addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; risks from concomitant use with benzodiazepines or other cns depressants; ultrarapid metabolism of codeine and other risk factors for life threatening respiratory depression in children; neonatal opioid withdrawal syndrome; interactions with drugs affecting cytochrome p450 isoenzymes; and hepatotoxicity
Acetaminophen / Codeine: Acetaminophen / Codeine Warnings: Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death; death related to ultra-rapid metabolism of codeine to morphine ; respiratory depression and death have occurred in children who received codeine following tonsillectomy and/or adenoidectomy and had evidence of being ultra-rapid metabolizers of codeine due to a CYP2D6 polymorphism.
Acetaminophen / Hydrocodone: Acetaminophen / Hydrocodone Warnings: respiratory depression; head injury and increased intracranial pressure; narcotics produce adverse reactions which may obscure the clinical course of patients with head injuries; acute abdominal conditions
Acetaminophen / Hydrocodone [Norco]: Acetaminophen / Hydrocodone [Norco] Warnings: addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; cytochrome p450 3a4 interaction; hepatotoxicity; and risks from concomitant use with benzodiazepines or other cns depressants
Acetaminophen / Oxycodone [Percocet]: Acetaminophen / Oxycodone [Percocet] Warnings: addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; cytochrome p450 3a4 interaction; hepatotoxicity; and risks from concomitant use with benzodiazepines or other cns depressants
Acetaminophen / Oxycodone [Xartemis]: Acetaminophen / Oxycodone [Xartemis] Warnings: addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; cytochrome p450 3a4 interaction; hepatotoxicity; and risks from concomitant use with benzodiazepines or other cns depressants
Acetaminophen / Tramadol [Ultracet]: Acetaminophen / Tramadol [Ultracet] Warnings: addiction , abuse, and misuse; life-threatening respiratory depression; accidential ingestion; neonatal opioid withdrawal syndrome; interation with drugs affecting cytochrome p450 isoenzymes; and risks from concomitant use with benzodiazepines or other cns depressants
Acetaminophen Injection [Ofirmev]: Acetaminophen Injection [Ofirmev] Warnings: risk of medication errors and hepatotoxicity
Acetaminophen-containing products: Acetaminophen-containing products Warnings: potential for severe liver injury and a warning highlighting the potential for allergic reactions (e.g., swelling of the face, mouth, and throat, difficulty breathing, itching, or rash)
Acetylsalicylic acid / Oxycodone [Percodan]: Acetylsalicylic acid / Oxycodone [Percodan] Warnings: addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; cytochrome p450 3a4 interaction; and risks from concomitant use with benzodiazepines or other cns depressants
Acitretin [Soriatane]: Acitretin [Soriatane] Warnings: contraindications and warnings: pregnancy
Adalimumab [Humira]: Adalimumab [Humira] Warnings: serious infections and malignancy
Adalimumab-adbm [Cyltezo]: Adalimumab-adbm [Cyltezo] Warnings: serious infections and malignancy
Adalimumab-atto [Amjevita]: Adalimumab-atto [Amjevita] Warnings: serious infections and malignancy
Adefovir Dipivoxil [Hepsera]: Adefovir Dipivoxil [Hepsera] Warnings: severe acute exacerbations of hepatitis, nephrotoxicity, hiv resistance, lactic acidosis and severe hepatomegaly with steatosis
Ado-trastuzumab [Kadcyla]: Ado-trastuzumab [Kadcyla] Warnings: hepatotoxicity, cardiac toxicity, embryo-fetal toxicity
Aflibercept [Zaltrap]: Aflibercept [Zaltrap] Warnings: hemorrhage, gastrointestinal develops perforation, compromised wound healing
Albiglutide [Tanzeum]: Albiglutide [Tanzeum] Warnings: risk of thyroid c-cell tumors
Aldesleukin [Proleukin]: Aldesleukin [Proleukin] Warnings: therapy with proleukin® (aldesleukin) should be restricted to patients with normal cardiac and pulmonary functions as defined by thallium stress testing and formal pulmonary function testing. extreme caution should be used in patients with a normal thallium stress test and a normal pulmonary function test who have a history of cardiac or pulmonary disease.
Alemtuzumab [Campath]: Alemtuzumab [Campath] Warnings: cytopenias, infusion reactions, and infections
Alemtuzumab [Lemtrada]: Alemtuzumab [Lemtrada] Warnings: autoimmunity, infusion reactions, and malignancies
Alfentanil [Alfenta]: Alfentanil [Alfenta] Warnings: alfenta should be administered only by persons specifically trained in the use of intravenous and general anesthetic agents and in the management of respiratory effects of potent opioids
Alglucosidase alfa [Lumizyme]: Alglucosidase alfa [Lumizyme] Warnings: risk of anaphylaxis, hypersensitivity and immune-mediated reactions, and risk of cardiorespiratory failure
Alglucosidase alfa [Myozyme]: Alglucosidase alfa [Myozyme] Warnings: risk of anaphylaxis, hypersensitivity and immune-mediated reactions, and risk of cardiorespiratory failure
Aliskiren / Amlodipine / HCTZ [Amturnide]: Aliskiren/Amlodipine/HCTZ [Amturnide] Warnings: fetal toxicity
Aliskiren / Amlodipine [Tekamlo]: Aliskiren/Amlodipine [Tekamlo] Warnings: fetal toxicity
Aliskiren / Hydrochlorothiazide [Tekturna Hct]: Aliskiren / Hydrochlorothiazide [Tekturna Hct] Warnings: fetal toxicity
Aliskiren / Valsartan [Valturna]: Aliskiren/Valsartan [Valturna] Warnings: fetal toxicity
Aliskiren [Tekturna]: Aliskiren [Tekturna] Warnings: fetal toxicity
Allergen extract [Grastek]: Allergen extract [Grastek] Warnings: severe allergic reactions
Allergen extract [Oralair]: Allergen extract [Oralair] Warnings: severe allergic reactions
Allergen extract [Ragwitek]: Allergen extract [Ragwitek] Warnings: severe allergic reactions
Allopurinol / Lesinurad [Duzallo]: Allopurinol / Lesinurad [Duzallo] Warnings: risk of acute renal failure.
Alogliptin / Pioglitazone [Oseni]: Alogliptin / Pioglitazone [Oseni] Warnings: congestive heart failure
Alosetron HCl [Lotronex]: Alosetron HCl [Lotronex] Warnings: serious gastrointestinal adverse reactions
Alprazolam [Xanax]: Alprazolam [Xanax] Warnings: risks from concomitant use with opioids
Alprostadil [Prostin VR Pediatric]: Alprostadil [Prostin VR Pediatric] Warnings: apnea is experienced by about 10 to 12% of neonates with congenital heart defects treated with alprostadil injection. Apnea is most often seen in neonates weighing less than 2 kg at birth and usually appears during the first hour of drug infusion. Therefore, respiratory status should be monitored throughout treatment, and alprostadil injection should be used where ventilatory assistance is immediately available.
Altretamine [Hexalen]: Altretamine [Hexalen] Warnings: should only be given under the supervision of a physician experienced in the use of antineoplastic agents.
Alvimopan [Entereg]: Alvimopan [Entereg] Warnings: potential risk of myocardial infarction with long-term use: for short-term hospital use only
Ambrisentan [Letairis]: Ambrisentan [Letairis] Warnings: embryo-fetal toxicity
Amikacin: Amikacin Warnings: patients treated with parenteral aminoglycosides should be under close clinical observation because of the potential ototoxicity and nephrotoxicity associated with their use. Safety for treatment periods which are longer than 14 days has not been established.
Amino acid / electrolyte / dextrose / lipid injectable [Kabiven]: Amino acid / electrolyte / dextrose / lipid injectable [Kabiven] Warnings: death in preterm infants
Amiodarone [Cordarone]: Amiodarone [Cordarone] Warnings: amiodarone is intended for use only in patients with the indicated life-threatening arrhythmias because its use is accompanied by substantial toxicity. …
Amitriptyline: Amitriptyline Warnings: suicidality and antidepressant drugs: antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (mdd) and other psychiatric disorders. ….
Amlodipine / Olmesartan [Azor]: Amlodipine / Olmesartan [Azor] Warnings: fetal toxicity
Amlodipine / Perindopril [Prestalia]: Amlodipine / Perindopril [Prestalia] Warnings: fetal toxicity
Amoxapine: Amoxapine Warnings: suicidality and antidepressant drugs: antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (mdd) and other psychiatric disorders.
Amphetamine: Amphetamine Warnings: abuse and dependence: cns stimulants, including adzenys xr-odt, other amphetamine-containing products, and methylphenidate, have a high potential for abuse and dependence. …
Amphetamine / Dextroamphetamine [Adderall XR]: Amphetamine / Dextroamphetamine [Adderall XR] Warnings: high abuse/diversion potential, serious adverse effects
Amphetamine / Dextroamphetamine [Mydayis]: Amphetamine / Dextroamphetamine [Mydayis] Warnings: high abuse/diversion potential, serious adverse effects
amphetamine [Adzenys ER]: amphetamine [Adzenys ER] Warnings: abuse and dependence
Amphotericin B [Fungizone]: Amphotericin B [Fungizone] Warnings: this drug should be used primarily for treatment of patients with progressive and potentially life-threatening fungal infections; it should not be used to treat noninvasive forms of fungal disease such as oral thrush, vaginal candidiasis and esophageal candidiasis in patients with normal neutrophil counts. …
Anadrol-50 [oxymetholone]: Anadrol-50 [oxymetholone] Warnings: peliosis hepatis, liver cell tumors, blood lipid changes
Anthrax Immune Globulin [Anthrasil]: Anthrax Immune Globulin [Anthrasil] Warnings: interactions with glucose monitoring systems and thrombosis
Anti-inhibitor Coagulant Complex [Feiba VH]: Anti-inhibitor Coagulant Complex [Feiba VH] Warnings: products made from plasma may contain infectious agents, such as viruses.
Anti-thymocyte Globulin (rabbit) [Thymoglobulin]: Anti-thymocyte Globulin (rabbit) [Thymoglobulin] Warnings: thymoglobulin should only be used by physicians experienced in immunosuppressive therapy for the management of renal transplant patients.
Anti-thymocyte Globulin [equine]/lymphocyte immune globulin [Atgam]: Anti-thymocyte Globulin [equine]/lymphocyte immune globulin [Atgam] Warnings: only physicians experienced in immunosuppressive therapy in the treatment of renal transplant or aplastic anemia patients should use atgam.
Apixaban [Eliquis]: Apixaban [Eliquis] Warnings: (a) premature discontinuation of eliquis increases the risk of thrombotic events (b) spinal/epidural hematoma
Aprotinin [Trasylol]: Aprotinin [Trasylol] Warnings: adminstration may cause fatal anaphylactic or anaphylactoid reactions.
Arformoterol [Brovana]: Arformoterol [Brovana] Warnings: asthma related death
Aripiprazole [Abilify Maintena]: Aripiprazole [Abilify Maintena] Warnings: increased mortality in elderly patients with dementia-related psychosis and suicidal thoughts and behaviors with antidepressant drugs
Aripiprazole [Abilify MyCite]: Aripiprazole [Abilify MyCite] Warnings: increased mortality in elderly patients with dementia-related psychosis and suicidal thoughts and behaviors with antidepressant drugs
Aripiprazole [Abilify]: Aripiprazole [Abilify] Warnings: increased mortality in elderly patients with dementia-related psychosis and suicidal thoughts and behaviors with antidepressant drugs
Aripiprazole [Aristada]: Aripiprazole [Aristada] Warnings: increased mortality in elderly patients with dementia-related psychosis.
Aripirazole [Abilify Mycite]: Aripirazole [Abilify Mycite] Warnings: increased mortality in elderly patients with dementioa related psychosi
Armodafinil [Nuvigil]: Armodafinil [Nuvigil] Warnings: serious rash, angiodema, multi-organ hypersensitivity reactions, persistent sleepiness, psychiatric symptoms, effects on ability to drive and use machinery, and cardiovascular events.
Arsenic Trioxide [Trisenox]: Arsenic Trioxide [Trisenox] Warnings: apl differentiation syndrome, cardiac conduction abnormalities, and electrolyte monitoring
Asenapine: Asenapine Warnings: increased mortality in elderly patients with dementia-related psychosis
Aspirin: Aspirin Warnings: reyess syndrome, allergic reactions, alcohol warning.
Aspirin / Caffeine / Dihydrocodeine Bitartrate [Synalgos-DC]: Aspirin / Caffeine / Dihydrocodeine Bitartrate [Synalgos-DC] x Warnings: Death related to ultra-rapid metabolism of codeine to morphine
Atenolol: Atenolol Warnings: cessation of therapy with atenolol
Ativan [lorazepam]: Ativan [lorazepam] Warnings: risks from concomitant use with opioids
Atomoxetine [Strattera]: Atomoxetine [Strattera] Warnings: suicidal ideation in children and adolescents
Axicabtagene Ciloleucel [Yescarta]: Axicabtagene Ciloleucel [Yescarta] Warnings: cytokine release syndrome and neurologic toxicities
Azathioprine [Imuran]: Azathioprine [Imuran] Warnings: malignancy
Azilsartan medoxomil [Edarbi]: Azilsartan medoxomil [Edarbi] Warnings: fetal toxicity
Bacillus Calmette and Gu+C3446érin BCG [Live] : Bacillus Calmette and Gu+C3446érin BCG [Live] Warnings: bcg contains live, attenuated mycobacteria. Because of the potential risk for transmission, it should be prepared, handled, and disposed of as a biohazard material.
Bacitracin Injection [Baci-IM]: Bacitracin Injection [Baci-IM] Warnings: nephrotoxicity: bacitracin in parenteral (intramuscular) therapy may cause renal failure due to tubular and glomerular necrosis.
Baclofen [Gablofen]: Baclofen [Gablofen] Warnings: do not discontinue abruptly
Baclofen [Lioresal]: Baclofen [Lioresal] Warnings: do not discontinue abruptly
Basiliximab [Simulect]: Basiliximab [Simulect] Warnings: only physicians experienced in immunosuppression therapy and management of organ transplantation patients should prescribe basiliximab.
Bazedoxifene / Conjugated estrogens [Duavee]: Bazedoxifene / Conjugated estrogens [Duavee] Warnings: endometrial cancer,cardiovascular disorders, and probable dementia
BCG Live [TICE BCG]: BCG Live [TICE BCG] Warnings: bcg contains live, attenuated mycobacteria. Because of the potential risk for transmission, it should be prepared, handled, and disposed of as a biohazard material.
Becaplermin [Regranex]: Becaplermin [Regranex] Warnings: increased rate of mortality secondary to malignancy
Bedaquiline [Sirturo]: Bedaquiline [Sirturo] Warnings: increased mortality; qt prolongation
Belatacept [Nulojix]: Belatacept [Nulojix] Warnings: post-transplant lymphoproliferative disorder, other malignancies, and serious infections
Benazepril: Benazepril Warnings: use in pregnancy: when used in pregnancy during the second and third trimesters, ace inhibitors can cause injury and even death to the developing fetus.
Benzathine benzylpenicillin [Bicillin L-A]: Benzathine benzylpenicillin [Bicillin L-A] Warnings: not for intravenous use.
Benzylpenicillin (aka Penicillin G): Benzylpenicillin Serious and occasionally fatal hypersensitivity (anaphylactoid) reactions have been reported in patients on penicillin therapy.
Betrixaban [Bevyxxa]: Betrixaban [Bevyxxa] Warnings: spinal/epidural hematoma
Bevacizumab [Avastin]: Bevacizumab [Avastin] Warnings: gastrointestinal perforations, surgery and wound healing complications, and hemorrhage
Bexarotene [Targretin]: Bexarotene [Targretin] Warnings: bexarotene capsules are a member of the retinoid class of drugs that is associated with birth defects in humans. Bexarotene capsules also caused birth defects when administered orally to pregnant rats. Bexarotene capsules must not be administered to a pregnant woman
Bismuth Subcitrate / Metronidazole / Tetracycline [Pylera]: Bismuth Subcitrate / Metronidazole / Tetracycline [Pylera] Warnings: potential for carcinogenicity
Bleomycin: Bleomycin Warnings: it is recommended that bleomycin for injection, usp be administered under the supervision of a qualified physician experienced in the use of cancer chemotherapeutic agents.  Appropriate management of therapy and complications is possible only when adequate diagnostic and treatment facilities are readily available.
Blinatumomab [Blincyto]: Blinatumomab [Blincyto] Warnings: cytokine release syndrome and neurological toxicities
Bosentan [Tracleer]: Bosentan [Tracleer] Warnings: risks of hepatotoxicity and embryo-fetal toxicity
Botox Cosmetic OnabotulinumtoxinA: Botox Cosmetic OnabotulinumtoxinA Warnings: distant spread of toxin effect
Botox OnabotulinumtoxinA: Botox OnabotulinumtoxinA Warnings: distant spread of toxin effect
Botulinum Toxin Type A [Dysport]: Botulinum Toxin Type A [Dysport] Warnings: distant spread of toxin effect
Botulinum Toxin Type A [Xeomin]: Botulinum Toxin Type A [Xeomin] Warnings: distant spread of toxin effect
Botulinum Toxin Type B [Myobloc]: Botulinum Toxin Type B [Myobloc] Warnings: distant spread of toxin effect
Brentuximab [Adcetris]: Brentuximab [Adcetris] Warnings: progressive multifocal leukoencephalopathy (pml)
Brexpiprazole [Rexulti]: Brexpiprazole [Rexulti] Warnings: increased mortality in elderly patients with dementia-related psychosis; and suicidal thoughts and behaviors.
Brodalumab [Siliq]: Brodalumab [Siliq] Warnings: suicidal ideation and behavior
Budesonide / Formoterol [Symbicort]: Budesonide / Formoterol [Symbicort] Warnings: astham-related death
Budesonide [Pulmicort]: Budesonide [Pulmicort] Warnings: localized infections, deterioration of asthma, hypersensitivity reactions, immunosuppression, …
Bupivacaine [Marcaine]: Bupivacaine [Marcaine] Warnings: the 0.75% concentration of bupivacaine hydrochloride is not recommended for obstetrical anesthesia. There have been reports of cardiac arrest with difficult resuscitation or death during use of bupivacaine hydrochloride for epidural anesthesia in obstetrical patients.
Bupivacaine [Sensorcaine]: Bupivacaine [Sensorcaine] Warnings: the 0.75% concentration of bupivacaine hydrochloride is not recommended for obstetrical anesthesia. There have been reports of cardiac arrest with difficult resuscitation or death during use of bupivacaine hydrochloride for epidural anesthesia in obstetrical patients.
Buprenorphine Buccal Film [Belbuca]: Buprenorphine Buccal Film [Belbuca] Warnings: addiction, abuse, and misuse; life-threatening respiratory depression; accidental exposure; and neonatal opioid withdrawal syndrome; and risks from concomitant use with benzodiazepines or other cns depressants
Buprenorphine Extended-Release Injection [Sublocade]: Buprenorphine Extended-Release Injection [Sublocade] Warnings: risk of serious harm or death with intravenous administration
Buprenorphine Implant [Probuphine]: Buprenorphine Implant [Probuphine] Warnings: implant migration, protrusion, expulsion, and nerve damage associated with insertion and removal
Buprenorphine Transdermal [Butrans]: Buprenorphine Transdermal [Butrans] Warnings: addiction, abuse, and misuse; life-threatening respiratory depression; accidental exposure; and neonatal opioid withdrawal syndrome; and risks from concomitant use with benzodiazepines or other cns depressants
Bupropion [Aplenzin]: Bupropion [Aplenzin] Warnings: suicidal thoughts and behaviors
Bupropion [Forfivo XL]: Bupropion [Forfivo XL] Warnings: suicidal thoughts and behaviors; and neuropsychiatric reactions
Bupropion [Wellbutrin]: Bupropion [Wellbutrin] Warnings: suicidal thoughts and behaviors.
Bupropion [Zyban]: Bupropion [Zyban] Warnings: suicidal thoughts and behaviors; and neuropsychiatric reactions
Bupropion/Naltrexone [Contrave]: Bupropion/Naltrexone [Contrave] Warnings: suicidal thoughts and behaviors.
Busulfan [Busulfex]: Busulfan [Busulfex] Warnings: myelosuppression
Busulfan [Myleran]: Busulfan [Myleran] Warnings: myleran is a potent drug. It should not be used unless a diagnosis of chronic myelogenous leukemia has been adequately established and the responsible physician is knowledgeable in assessing response to chemotherapy.
Butorphanol [Stadol]: Butorphanol [Stadol] ddiction, abuse, and misuse; physical dependence, tolerance, and withdrawal
Bydureon BCISE: Bydureon BCISE Warnings: risk of thyroid c-cell tumors
Cabazitaxel [Jevtana]: Cabazitaxel [Jevtana] Warnings: neutropenia and hypersensitivity
Cabozantinib [Cometriq]: Cabozantinib [Cometriq] Warnings: perforations and fistulas, and hemorrhage
Calcium Chloride / Icodextrin / Lactic Acid / Magnesium chloride / Sodium Chloride [Extraneal]: Calcium Chloride / Icodextrin / Lactic Acid / Magnesium chloride / Sodium Chloride [Extraneal] Warnings: unrecognized hypoglycemia resulting from drug-device interaction
Canagliflozin / Metformin [Invokamet XR]: Canagliflozin / Metformin [Invokamet XR] Warnings: lactic acidosis and lower limb amputation
Canagliflozin / Metformin [Invokamet]: Canagliflozin / Metformin [Invokamet] Warnings: lactic acidosis and lower limb amputation
Canagliflozin [Invokana]: Canagliflozin [Invokana] Warnings: lower limb amputation
Candesartan: Candesartan Warnings: fetal toxicity
Capecitabine [Xeloda]: Capecitabine [Xeloda] Warnings: capecitabine-warfarin interaction
Capreomycin [Capastat]: Capreomycin [Capastat] the use of capastat sulfate (capreomycin for injection, usp) in patients with renal insufficiency or preexisting auditory impairment must be undertaken with great caution, and the risk of additional cranial nerve viii impairment or renal injury should be weighed against the benefits to be derived from therapy.
Captopril: Captopril Warnings: fetal toxicity
Carbamazepine [Carbatrol]: Carbamazepine [Carbatrol] Warnings: serious dermatologic reactions and hla-b*1502 allele  serious and sometimes fatal dermatologic reactions, including toxic epidermal necrolysis (ten) and stevens-johnson syndrome (sjs), have been reported during treatment with carbamazepine.
Carbamazepine [Carnexiv]: Carbamazepine [Carnexiv] Warnings: serious dermatologic reactions and aplastic anemia and agranulocytosis.
Carbamazepine [Equetro]: Carbamazepine [Equetro] Warnings: serious dermatologic reactions and aplastic anemia and agranulocytosis.
Carbamazepine [Tegretol]: Carbamazepine [Tegretol] Warnings: serious dermatologic reactions and hla-b*1502 allele
Carbidopa [Lodosyn]: Carbidopa [Lodosyn] Warnings: carbidopa has no antiparkinsonian effect when given alone. It is indicated for use with carbidopa-levodopa or levodopa. Carbidopa does not decrease adverse reactions due to central effects of levodopa; falling asleep during activities of daily living and somnolence; hyperpyrexia and confusion
Carbonyl iron [Ferralet]: Carbonyl iron [Ferralet] Warnings: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6.
Carboplatin [Paraplatin]: Carboplatin [Paraplatin] Warnings: carboplatin injection should be administered under the supervision of a qualified physician experienced in the use of cancer chemotherapeutic agents. Appropriate management of therapy and complications is possible only when adequate treatment facilities are readily available.
Cariprazine [Vraylar]: Cariprazine [Vraylar] Warnings: increased mortality in elderly patients with dementia-related psychosis
Carmustine [BiCNU]: Carmustine [BiCNU] Warnings: myelosuppression and pulmonary toxicity
Celecoxib: Celecoxib Warnings: risk of serious cardiovascular and gastrointestinal events
Certolizumab [Cimzia]: Certolizumab [Cimzia] Warnings: serious infections and malignancy
Cetuximab [Erbitux]: Cetuximab [Erbitux] Warnings: serious infusion reactions and cardiopulmonary arrest
Chlorambucil [Leukeran]: Chlorambucil [Leukeran] Warnings: leukeran (chlorambucil) can severely suppress bone marrow function. Chlorambucil is a carcinogen in humans. Chlorambucil is probably mutagenic and teratogenic in humans. Chlorambucil produces human infertility (see warnings and precautions).
Chloramphenicol: Chloramphenicol Warnings: serious and fatal blood dyscrasias (aplastic anemia, hypoplastic anemia, thrombocytopenia and granulocytopenia) are known to occur after the administration of chloramphenicol.  in addition, there have been reports of aplastic anemia attributed to chloramphenicol which later terminated in leukemia.
Chlordiazepoxide: Chlordiazepoxide chlordiazepoxide may impair the mental and/or physical abilities required for the performance of potentially hazardous tasks such as driving a vehicle or operating machinery. Similarly, it may Warnings: chlordiazepoxide impair mental alertness in children. The concomitant use of alcohol or other central nervous system depressants may have an additive effect. Patients should be warned accordingly.
Chlordiazepoxide-Clidinium [Librax]: Chlordiazepoxide-Clidinium [Librax] Warning: Concomitant use of benzodiazepines and opioids may result in profound sedation, respiratory depression, coma, and death
Chloroquine: Chloroquine Warnings: for malaria and extraintestinal amebiasis
Chlorphenamine / Codeine: Chlorphenamine / Codeine Warnings: death related to ultra-rapid metabolism of codeine to morphine andrisks from concomitant use with benzodiazepines or other cns depressants
Chlorphenamine / Hydrocodone [Tussionex]: Chlorphenamine / Hydrocodone [Tussionex] Warnings: risks from concomitant use with benzodiazepines or other cns depressants.
Chlorpheniramine / Codiene [Tuxarin ER]: Chlorpheniramine / Codiene [Tuxarin ER] Warnings: ultra-rapid metabolism of codeine and other risk factors for life-threatening respiratory depression in children and risks from concomitant use with benzodiazepines or other cns depressants
Chlorpromazine: Chlorpromazine Warnings: increased mortality in elderly patients with dementia-related psychosis
Chorionic Gonadotropin (Human) [Pregnyl]: Chorionic Gonadotropin (Human) [Pregnyl] warnings: hcg should be used in conjunction with human menopausal gonadotropins only by physicians experienced with infertility problems who are familiar with the criteria for patient selection, contraindications, warnings, precautions, and adverse reactions described in the package insert for menotropins. Anaphylaxis has been reported with urinary-derived hcg products.
Cidofovir [Vistide]: Cidofovir [Vistide] Warnings: renal impairment is the major toxicity
Cilostazol [Pletal]: Cilostazol [Pletal] Warnings: contraindication cilostazol and several of its metabolites are inhibitors of phosphodiesterase iii. Several drugs with this pharmacologic effect have caused decreased survival compared to placebo in patients with class iii to iv congestive heart failure. Cilostazol is contraindicated in patients with congestive heart failure of any severity.
Cipro [ciprofloxacin]: Cipro [ciprofloxacin] Warnings: serious adverse reactions including tendinitis, tendon rupture, peripheral neuropathy, central nervous system effects and exacerbation of myasthenia gravis
Cisplatin [Platinol]: Cisplatin [Platinol] Warnings: cisplatin should be administered under the supervision of a qualified physician experienced in the use of cancer chemotherapeutic agents. Appropriate management of therapy and complications is possible only when adequate diagnostic and treatment facilities are readily available.
Citalopram: Citalopram Warnings: suicidality and antidepressant drugs
Cladribine [Leustatin]: Cladribine [Leustatin] Warnings: cladribine injection should be administered under the supervision of a qualified physician experienced in the use of antineoplastic therapy.
Clindamycin [Cleocin]: Clindamycin [Cleocin] Warnings: clostridium difficile associated diarrhea (cdad) has been reported with use of nearly all antibacterial agents, including clindamycin and may range in severity from mild diarrhea to fatal colitis. Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of c. Difficile
Clobazam [Onfi]: Clobazam [Onfi] Warnings: risk from concomitant use with opioids
Clomipramine: Clomipramine Warnings: suicidality and antidepressant drugs
Clonazepam [Klonopin]: Clonazepam [Klonopin] Warning: Risk from concomitant use with opioids
Clonidine Injection [Duraclon]: Clonidine Injection [Duraclon] Warnings: clonidine hydrochloride injection (epidural clonidine) is not recommended for obstetrical, postpartum, or perioperative pain management.
Clopidogrel [Plavix]: Clopidogrel [Plavix] Warnings: diminished antiplatelet effect in patients with two loss-of-function alleles of the cyp2c19 gene
Clorazepate [Gen-xene, Tranxene]: Clorazepate [Gen-xene, Tranxene] Warnings: risk from concomitant use with opioids
Clozapine [Clozaril]: Clozapine [Clozaril] Warnings: severe neutropenia; orthostatic hypotension, bradycardia, and syncope; seizure; myocarditis and cardiomyopathy; increased mortality in elderly patients with dementia-related psychosis
Clozapine [Fazaclo]: Clozapine [Fazaclo] Warnings: severe neutropenia; orthostatic hypotension, bradycardia, and syncope; seizure; myocarditis and cardiomyopathy; increased mortality in elderly patients with dementia-related psychosis
Clozapine [Versacloz]: Clozapine [Versacloz] Warnings: severe neutropenia; orthostatic hypotension, bradycardia, and syncope; seizure; myocarditis and cardiomyopathy; increased mortality in elderly patients with dementia-related psychosis
Cobicistat / Elvitegravir / Emtricitabine / Tenofovir alafenamide [Genvoya]: Cobicistat / Elvitegravir / Emtricitabine / Tenofovir alafenamide [Genvoya] Warnings: post treatment acute exacerbation of hepatitis b
Cobicistat / Elvitegravir / Emtricitabine / Tenofovir disoproxil [Stribild]: Cobicistat / Elvitegravir / Emtricitabine / Tenofovir disoproxil [Stribild] Warnings: post treatment acute exacerbation of hepatitis b
Codeine / Promethazine: Codeine / Promethazine Warnings: ultra-rapid metabolism of codeine and other risk factors for life-threatening respiratory depression in children and risks from concomitant use with benzodiazepines or other cns depressants.
Codeine tablets: Codeine tablets Warnings: addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; death related to ultra-rapid metabolism of codeine to morphine; interactions with drugs affecting cytochrome p450 isoenzymes; and risks from concomitant use with benzodiazepines or other cns depressants
Collagenase clostridium histolyticum: Collagenase clostridium histolyticum Warnings: corporal rupture (penile fracture) or other serious penile injury in the treatment of peyronie’s disease
Conjugated estrogens / Medroxyprogesterone acetate [Prempro 0.625/2.5 28 Day]: Conjugated estrogens / Medroxyprogesterone acetate [Prempro 0.625/2.5 28 Day] Warnings: cardiovascular disorders, breast cancer, endometrial cancer and probable dementia
Conjugated estrogens [Premarin]: Conjugated estrogens [Premarin] Warnings: endometrial cancer, cardiovascular disorders, breast cancer, and probable dementia
Cyclosporine: Cyclosporine Warnings: only physicians experienced in management of systemic immunosuppressive therapy for the indicated disease should prescribe cyclosporine capsules usp (modified).
Cyclosporine [Neoral]: Cyclosporine [Neoral] Warnings: only physicians experienced in management of systemic immunosuppressive therapy for the indicated disease should prescribe cyclosporine capsules usp (modified).
Cyclosporine [Sandimmune]: Cyclosporine [Sandimmune] Warnings: only physicians experienced in management of systemic immunosuppressive therapy for the indicated disease should prescribe cyclosporine capsules usp (modified).
Cytarabine: Cytarabine Warnings: only physicians experienced in cancer chemotherapy should use cytarabine injection
Cytarabine / Daunorubicin [Vyxeos]: Cytarabine / Daunorubicin [Vyxeos] Do not interchange with other daunorubicin and/or cytarabine containing products
Cytarabine [Depocyt.pdf]: Cytarabine [Depocyt.pdf] Warnings: chemical arachnoiditis adverse reactions
Dabigatran [Pradaxa]: Dabigatran [Pradaxa] Warnings: (a) premature discontinuation of pradaxa increases the risk of thrombotic events, (b) spinal/epidural hematoma
Dacarbazine [DTIC-Dome]: Dacarbazine [DTIC-Dome] Warnings: it is recommended that dacarbazine be administered under the supervision of a qualified physician experienced in the use of cancer chemotherapeutic agents.
Daclatasvir [Daklinza]: Daclatasvir [Daklinza] Warnings: risk of hepatitis b virus reactivation in patients coinfected with hcv and hbv
Daclizumab [Zinbryta]: Daclizumab [Zinbryta] Warnings: hepatic injury including autoimmune hepatitis and other immune-mediated disorders
Dactinomycin [Cosmegen] : Dactinomycin [Cosmegen] Warnings: dactinomycin for injection should be administered only under the supervision of a physician who is experienced in the use of cancer chemotherapeutic agents.
Dalfopristin / Quinupristin: Dalfopristin / Quinupristin Warnings: drug interactions
Dalteparin: Dalteparin Warnings: spinal/epidural hematomas
Danazol: Danazol Warnings: use of danazol in pregnancy is contraindicated; thromboembolism, thrombotic and thrombophlebitic events including sagittal sinus thrombosis and life-threatening or fatal strokes have been reported; danazol has been associated with several cases of benign intracranial hypertension also known as pseudotumor cerebri.
Dantrolene [Dantrium]: Dantrolene [Dantrium] Warnings: dantrium (dantrolene sodium) has a potential for hepatotoxicity, and should not be used in conditions other than those recommended. Symptomatic hepatitis (fatal and non-fatal) has been reported at various dose levels of the drug.
Dapagliflozin / Metformin: Dapagliflozin / Metformin Warnings: lactic acidosis
Darbepoetin alfa [Aranesp]: Darbepoetin alfa [Aranesp] Warnings: esas increase the risk of death, myocardial infarction, stroke, venous thromboembolism, thrombosis of vascular access and tumor progression or recurrence
Dasabuvir / Ombitasvir / Paritaprevir / Ritonavir [Viekira Pak]: Dasabuvir / Ombitasvir / Paritaprevir / Ritonavir [Viekira Pak] Warnings: risk of hepatitis b virus reactivation in patients coinfected with hcv and hbv.
Dasabuvir / Ombitasvir / Paritaprevir / Ritonavir [Viekira XR Pak]: Dasabuvir / Ombitasvir / Paritaprevir / Ritonavir [Viekira XR Pak] Warnings: risk of hepatitis b virus reactivation in patients coinfected with hcv and hbv.
Daunorubicin: Daunorubicin Warnings: daunorubicin hydrochloride is a potent bone marrow suppressant.
Deferasirox [Exjade]: Deferasirox [Exjade] Warnings: renal failure, hepatic failure, and gastrointestinal hemorrhage
Deferasirox [Jadenu]: Deferasirox [Jadenu] Warnings: renal failure, hepatic failure, and gastrointestinal hemorrhage
Deferiprone [Ferriprox]: Deferiprone [Ferriprox] Warnings: agranulocytosis/neutropenia
Delafloxacin [Baxdela]: Delafloxacin [Baxdela] Warnings: serious adverse reactions including tendinitis, tendon rupture, peripheral neuropathy, cental nervous system effects, and exacerbation of myasthenia gravis
Denileukin Diftitox [Ontak]: Denileukin Diftitox [Ontak] Warnings: serious infusion reactions, capillary leak syndrome and loss of visual acuity.
Desipramine: Desipramine Warnings: suicidality and antidepressant drugs
Desirudin [Iprivask]: Desirudin [Iprivask] Warnings: spinal/epidural hematomas
Desmopressin nasal spray [Noctiva]: Desmopressin nasal spray [Noctiva] warnings: very rare cases of hyponatremia have been reported from world-wide postmarketing experience in patients treated with; ddavp (desmopressin acetate). Ddavp is a potent antidiuretic which, when administered, may lead to water intoxication and/or hyponatremia; when ddavp tablets are administered, in particular in pediatric and geriatric patients, fluid intake should be adjusted downward to decrease the potential occurrence of water intoxication and hyponatremia; ddavp should be used with caution in patients with habitual or psychogenic polydipsia who may be more likely to drink excessive amounts of water, putting them at greater risk of hyponatremia.
Desogestrel / Ethinyl Estradiol [Pimtrea]: Desogestrel / Ethinyl Estradiol [Pimtrea] Warnings: cardiovascular risk associated with smoking
Desvenlafaxine: Desvenlafaxine Warnings: suicidal thoughts and behaviors
Deutetrabenazine [Austedo]: Deutetrabenazine [Austedo] Warnings: depression and suicidality in patients with huntington’s disease
Dexmethylphenidate [Focalin XR]: Dexmethylphenidate [Focalin XR] Warnings: drug dependence, serious cardiovascular events, sudden death and preexisting structural cardiac abnormalities or other serious heart problems
Dexmethylphenidate [Focalin]: Dexmethylphenidate [Focalin] Warnings: serious cardiovascular events, sudden death and preexisting structural cardiac abnormalities or other serious heart problems
Dextroamphetamine: Dextroamphetamine Warnings: amphetamines have a high potential for abuse. Administration of amphetamines for prolonged periods of time may lead to drug dependence and must be avoided
Dextropropoxyphene [Darvon]: Dextropropoxyphene [Darvon] Warnings: there have been numerous cases of accidental and intentional overdose with propoxyphene products either alone or in combination with other cns depressants, including alcohol.
Diatrizoate / Iodipamide Meglumine [Sinografin]: Diatrizoate / Iodipamide Meglumine [Sinografin] Warnings: sudden onset of bradycardia, hypotension, cardiac arrest and death have rarely been reported. Hypersensitivity reactions, which include sweating, flushing, pruritus, urticaria, skin rashes, arthralgia, respiratory distress, and circulatory collapse have occurred. Dizziness, syncope, hypotension, chills, fever, nausea, vomiting, and abdominal pain and tenderness are occasionally seen following instillation of the contrast medium,
Diatrizoate Meglumine / Sodium [Gastrografin]: Diatrizoate Meglumine / Sodium [Gastrografin] Warnings: dehydration, aspiration, and anaphylactic reactions .
Diatrizoate Meglumine [Cystografin]: Diatrizoate Meglumine [Cystografin Warnings: severe sensitivity reactions are more likely to occur in patients with a personal or family history of bronchial asthma, significant allergies, or previous reactions to contrast agents.
Diazepam [Diastat, Diastat Acudial, Valium]: Diazepam [Diastat, Diastat Acudial, Valium] Warnings: risk from concomitant use with opioids
Diclofenac / Misoprostol [Arthrotec]: Diclofenac / Misoprostol [Arthrotec] Warnings: risk of uterine rupture, abortion, premature birth, birth defects? and serious cardiovascular and gastrointestinal events.
Diclofenac [Dyloject]: Diclofenac [Dyloject] Warnings: cardiovascular /gastrointestinal risk
Diclofenac [Pennsaid]: Diclofenac [Pennsaid] Warnings: cardiovascular /gastrointestinal risk
Diclofenac Gel [Solaraze]: Diclofenac Gel [Solaraze] Warnings: risk of serious cardiovascular events
Didanosine [Videx EC]: Didanosine [Videx EC] Warnings: pancreatitis, lactic acidosis and hepatomegaly with steatosis
Didanosine [Videx]: Didanosine [Videx] Warnings: pancreatitis, lactic acidosis and hepatomegaly with steatosis
Dienogest / Estradiol: Dienogest / Estradiol Warning: Cigarette smoking and serious cardiovascular events
Diflunisal: Diflunisal Warnings: cardiovascular thrombotic events
Dihydrocodeine [plus aspirin] [Synalgos]: Dihydrocodeine [plus aspirin] [Synalgos] Warnings: addiction, abuse, and misuse; lifethreatening respiratory depression; accidental ingestion; ultra-rapid metabolism of dihydrocodeine and other risk factors for life-threatening respiratory depression in children; neonatal opioid withdrawal syndrome; interactions with drugs affecting cytochrome p450 isoenzymes; and risks from concomitant use with benzodiazepines or other cns depressants.
Dihydroergotamine [Migranal]: Dihydroergotamine [Migranal] Warnings: serious and/or life-threatening peripheral ischemia has been associated with the coadministration of dihydroergotamine with potent cyp 3a4 inhibitors including protease inhibitors and macrolide antibiotics. Because cyp 3a4 inhibition elevates the serum levels of dihydroergotamine, the risk for vasospasm leading to cerebral ischemia and/or ischemia of the extremities is increased. Hence, concomitant use of these medications is contraindicated.
Dinoprostone [Cervidil]: Dinoprostone [Cervidil] Warnings: dinoprostone vaginal insert should be administered only by trained obstetrical personnel in a hospital setting with appropriate obstetrical care facilities.
Dinutuximab [Unituxin]: Dinutuximab [Unituxin] Warnings: serious infusion reactions and neurotoxicity
Disopyramide [Norpace]: Disopyramide [Norpace] Warnings: negative inotropic properties; heart failure/hypotension; qrs widening; q-t prolongation; hypoglycemia; concomitant antiarrhythmic therapy; heart block; anticholinergic activity.
Disulfiram [Antabuse]: Disulfiram [Antabuse] Warnings: disulfiram should never be administered to a patient when he is in a state of alcohol intoxication, or without his full knowledge.
Docetaxel [Docefrez]: Docetaxel [Docefrez] Warnings: toxic deaths, hepatotoxicity, neutropenia, hypersensitivity reactions, and fluid retention
Docetaxel [Taxotere]: Docetaxel [Taxotere] Warnings: toxic deaths, hepatotoxicity, neutropenia, hypersensitivity reactions, and fluid retention
Dofetilide [Tikosyn]: Dofetilide [Tikosyn] Warnings: to minimize the risk of induced arrhythmia, patients initiated or re-initiated on dofetilide capsules should be placed for a minimum of 3 days in a facility that can provide calculations of creatinine clearance, continuous electrocardiographic monitoring, and cardiac resuscitation.
Dopamine: Dopamine Warnings: keep out of reach of children. in case of overdose, contact a physician or poison control center right away.
Doxepin: Doxepin Warnings: suicidality and antidepressant drugs
Doxorubicin [Adriamycin]: Doxorubicin [Adriamycin] Warnings: cardiomyopathy, secondary malignancies, extravasation and tissue necrosis, and severe myelosuppression.
Doxorubicin Liposome Injection [Doxil]: Doxorubicin Liposome Injection [Doxil] Warnings: cardiomyopathy and infusion-related reactions.
Dronedarone [Multaq]: Dronedarone [Multaq] Warnings: increased risk of death, stroke and heart failure in patients with decompensated heart failure or permanent atrial fibrillation
Droperidol [Inapsine]: Droperidol [Inapsine] Warnings: cases of qt prolongation and/or torsade de pointes have been reported in patients receiving droperidol at doses at or below recommended doses.  some cases have occurred in patients with no known risk factors for qt prolongation and some cases have been fatal.
Drospirenone / Estradiol [Angeliq 0.25/0.5 28 Day]: Drospirenone / Estradiol [Angeliq 0.25/0.5 28 Day] Warnings: cardiovascular disorders, breast cancer, endometrial cancer and probable dementia
Drospirenone / Ethinyl Estradiol / Levomefolic acid [Rajani]: Drospirenone / Ethinyl Estradiol / Levomefolic acid [Rajani] Warnings: cigarette smoking and serious cardiovascular events
Drospirenone / Ethinyl Estradiol [Yaz 28 Day]: Drospirenone / Ethinyl Estradiol [Yaz 28 Day] Warnings: cigarette smoking and serious cardiovascular events
Droxidopa [Northera]: Droxidopa [Northera] Warnings: supine hypertension
Dulaglutide [Trulicity]: Dulaglutide [Trulicity] Warnings: risk of thyroid c-cell tumors
Duloxetine [Cymbalta]: Duloxetine [Cymbalta] Warnings: suicidal thoughts and behaviors
Ecallantide [Kalbitor]: Ecallantide [Kalbitor] Warnings: anaphylaxis
Eculizumab [Soliris]: Eculizumab [Soliris] Warnings: serious meningococcal infections
Edetate Disodium [Endrate]: Edetate Disodium [Endrate]
Edoxaban [Savaysa]: Edoxaban [Savaysa] Warnings: (a) reduced efficacy in nonvalvular atrial fibrillation patients with creatinine clearance (crcl) > 95 ml/min (b) premature discontinuation of savaysa increases the risk of ischemic events (c) spinal/epidural hematoma
Efavirenz / Emtricitabine / Tenofovir [Atripla]: Efavirenz / Emtricitabine / Tenofovir [Atripla] Warnings: posttreatment exacerbation of hepatitis b
Elbasvir / Grazoprevir [Zepatier]: Elbasvir / Grazoprevir [Zepatier] Warnings: risk of hepatitis b virus reactivation in patients coinfected with hcv and hbv
Elosulfase alfa [Vimizim]: Elosulfase alfa [Vimizim] Warnings: risk of anaphylaxis
Eltrombopag [Promacta]: Eltrombopag [Promacta] Warnings: risk for hepatic decompensation in patients with chronic hepatitis c
Emicizumab-kxwh [Hemlibra]: Emicizumab-kxwh [Hemlibra] Warnings: thrombotic microangiopathy and thromboembolism.
Empagliflozin / Metformin [Synjardy]: Empagliflozin / Metformin [Synjardy] Warnings: lactic acidosis
Emtricitabine / Rilpivirine / Tenofovir alafenamide [Odefsey]: Emtricitabine / Rilpivirine / Tenofovir alafenamide [Odefsey] Warnings: post treatment acute exacerbation of hepatitis b
Emtricitabine / Rilpivirine / Tenofovir disoproxil [Complera]: Emtricitabine / Rilpivirine / Tenofovir disoproxil [Complera] Warnings: post treatment acute exacerbation of hepatitis b
Emtricitabine / Tenofovir alafenamide [Descovy]: Emtricitabine / Tenofovir alafenamide [Descovy] Warnings: post treatment acute exacerbation of hepatitis b
Emtricitabine / Tenofovir disoproxil [Truvada]: Emtricitabine / Tenofovir disoproxil [Truvada] Warnings: post treatment acute exacerbation of hepatitis b
Emtricitabine [Emtriva]: Emtricitabine [Emtriva] Warnings: post treatment acute exacerbation of hepatitis b
Enalapril: Enalapril Warnings: use in pregnancy, when used in pregnancy during the second and third trimesters, ace inhibitors can cause injury and even death to the developing fetus.
Enasidenib [Idhifa]: Enasidenib [Idhifa] Warnings: differentiation syndrome
Entecavir [Baraclude]: Entecavir [Baraclude] Warnings: severe acute exacerbations of hepatitis b, patients co-infected with hiv and hbv, and lactic acidosis and hepatomegaly
Epirubicin Injection [Ellence]: Epirubicin Injection [Ellence] Warnings: SEVERE OR LIFE-THREATENING HEMATOLOGICAL AND OTHER ADVERSE REACTIONS
Epoetin alfa [Epogen]: Epoetin alfa [Epogen] Warning: esas increase the risk of death, myocardial infarction, stroke, venous thromboembolism, thrombosis of vascular access and tumor progression or recurrence
Eprosartan: Eprosartan Warnings: fetal toxicity
Ertugliflozin / Metformin [Segluromet]: Ertugliflozin / Metformin [Segluromet] Warnings: lactic acidosis
Erythropoietin [Epogen]: Erythropoietin [Epogen] Warnings: esas increase the risk of death, myocardial infarction, stroke, venous thromboembolism, thrombosis of vascular access and tumor progression or recurrence.
Erythropoietin [Procrit]: Erythropoietin [Procrit] Warnings: esas increase the risk of death, myocardial infarction, stroke, venous thromboembolism, thrombosis of vascular access and tumor progression or recurrence.
Escitalopram: Escitalopram Warnings: suicidality and antidepressant drugs
Esomeprazole / Naproxen [Vimovo]: Esomeprazole / Naproxen [Vimovo] Warnings: RISK OF SERIOUS CARDIOVASCULAR AND GASTROINTESTINAL EVENTS
Estazolam: Estazolam Warnings: Risk From Concomitant Use With Opioids
Estradiol [Elestrin]: Estradiol [Elestrin] Warnings: endometraial cancer, cardiovascular disorders, breast cancer and probable dementia
Estradiol Transdermal Spray [Evamist]: Estradiol Transdermal Spray [Evamist] Warnings: endometraial cancer, cardiovascular disorders, breast cancer and probable dementia, and unintentional secondary exposure to estrogen.
Etanercept [Enbrel]: Etanercept [Enbrel] Warnings: serious infections and malignancies
Etanercept-szzs [Erelzi]: Etanercept-szzs [Erelzi] Warnings: serious infections and malignancies
Ethinyl Estradiol / Etonogestrel [Nuvaring]: Ethinyl Estradiol / Etonogestrel [Nuvaring] Warnings: cigarette smoking and serious cardiovascular events
Ethinyl Estradiol / Norelgestromin [Ortho Evra]: Ethinyl Estradiol / Norelgestromin [Ortho Evra] Warnings: CARDIOVASCULAR RISK ASSOCIATED WITH SMOKING, RISK OF VENOUS THROMBOEMBOLISM, AND PHARMACOKINETIC PROFILE OF ETHINYL ESTRADIOL
Ethinyl estradiol / Norethindrone [Ortho-Novum/Modicon]: Ethinyl estradiol / Norethindrone [Ortho-Novum/Modicon] Warnings: CARDIOVASCULAR RISK ASSOCIATED WITH SMOKING
Ethinyl Estradiol / Norethisterone [Femhrt 0.5/2.5 28 Day]: Ethinyl Estradiol / Norethisterone [Femhrt 0.5/2.5 28 Day] Warnings: cardiovascular disorders, breast cancer, endometrial cancer and probable dementia
Etodolac: Etodolac Warnings: cardiovascular thrombotic events – nonsteroidal anti-inflammatory drugs (nsaids) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction …
Etoposide [Etopophos]: Etoposide [Etopophos] Warnings: myelosuppression, secondary leukemias, hypersensitivity reactions, embryo-fetal toxicity.
Everolimus [Zortress]: Everolimus [Zortress] Warning: malignancies and serious infections, kidney graft thrombosis; nephrotoxicity; and mortality in heart transplantation
Exenatide [Bydureon]: Exenatide [Bydureon] Warnings: risk of thyroid c-cell tumors
Exenatide Synthetic [Bydureon Bcise]: Exenatide Synthetic [Bydureon Bcise] Warnings: risk of tyroid c-cell tumors
Ezogabine [Potiga]: Ezogabine [Potiga] Warnings: retinal abnormalities and potential vision loss
Famotidine / Ibuprofen [Duexis]: Famotidine / Ibuprofen [Duexis] Warnings: Cardiovascular, gastrointestinal risk
Felbamate [Felbatol]: Felbamate [Felbatol] Warnings: plastic anemia; hepatic failure
Fenoprofen: Fenoprofen Warnings: cardiovascular thrombotic events – nonsteroidal anti-inflammatory drugs (nsaids) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction …
Fentanyl [Actiq]: Fentanyl [Actiq] Warnings: life-threatening respiratory depression; accidental ingestion; risks from cytochrome p450 3a4 interaction; risks from concomitant use with benzodiazepines or other cns depressants; risk of medication errors; addiction, abuse, and misuse; rems; and neonatal opioid withdrawal syndrome.
Fentanyl [Fentora]: Fentanyl [Fentora] Warnings: life-threatening respiratory depression; accidental ingestion; risks from cytochrome p450 3a4 interaction; risks from concomitant use with benzodiazepines or other cns depressants; risk of medication errors; addiction, abuse, and misuse; rems; and neonatal opioid withdrawal syndrome.
Fentanyl Buccal Film [Onsolis]: Fentanyl Buccal Film [Onsolis] Warnings: life-threatening respiratory depression; accidental ingestion; risks from cytochrome p450 3a4 interaction; risks from concomitant use with benzodiazepines or other cns depressants; risk of medication errors; addiction, abuse, and misuse; rems; and neonatal opioid withdrawal syndrome.
Fentanyl Nasal Spray [Lazanda]: Fentanyl Nasal Spray [Lazanda] Warnings: life-threatening respiratory depression; accidental ingestion; risks from cytochrome p450 3a4 interaction; risks from concomitant use with benzodiazepines or other cns depressants; risk of medication errors; addiction, abuse, and misuse; rems; and neonatal opioid withdrawal syndrome.
Fentanyl Sublingual Spray [Subsys]: Fentanyl Sublingual Spray [Subsys] Warnings: life-threatening respiratory depression; accidental ingestion; risks from cytochrome p450 3a4 interaction; risks from concomitant use with benzodiazepines or other cns depressants; risk of medication errors; addiction, abuse, and misuse; rems; and neonatal opioid withdrawal syndrome.
Fentanyl Sublingual Tablet [Abstral]: Fentanyl Sublingual Tablet [Abstral] Warnings: life-threatening respiratory depression; accidental ingestion; risks from cytochrome p450 3a4 interaction; risks from concomitant use with benzodiazepines or other cns depressants; risk of medication errors; addiction, abuse, and misuse; rems; and neonatal opioid withdrawal syndrome.
Fentanyl Transdermal [Duragesic]: Fentanyl Transdermal [Duragesic] Warnings: addiction, abuse, and misuse; lifethreatening respiratory depression; accidental exposure; neonatal opioid withdrawal syndrome; cytochrome p450 3a4 interaction; risk of increased fentanyl absorption with application of external heat; and risks from concomitant use of benzodiazepines or other cns depressants.
Ferumoxytol [Feraheme]: Ferumoxytol [Feraheme] Warnings: risk for serious hypersensitivity/anaphylaxis reactions
Flecainide: Flecainide Warnings: mortality; ventricular pro-arrhythmic effects in patients with atrial fibrillation/flutter
Flibanserin [Addyi]: Flibanserin [Addyi] Warnings: hypotension and syncope in certain settings
Floxuridine: Floxuridine Warnings: because of the possibility of severe toxic reactions, all patients should be hospitalized for the first course of therapy.
Flucytosine [Ancobon]: Flucytosine [Ancobon] Warnings: use with extreme caution in patients with impaired renal function.
Fludarabine: Fludarabine Warnings: fludarabine should be administered under the supervision of a qualified physician experienced in the use of antineoplastic therapy.
Flumazenil: Flumazenil Warnings: the use of flumazenil has been associated with the occurrence of seizures.
Fluoxetine: Fluoxetine Warnings: suicidality and antidepressant drugs
Fluoxetine / Olanzapine [Symbyax]: Fluoxetine / Olanzapine [Symbyax] Warnings: suicidal thoughts and behaviors; and increased mortality in elderly patients with dementia-related psychosis
Fluoxetine [Prozac Weekly]: Fluoxetine [Prozac Weekly] Warnings: suicidal thoughts and behaviors;
Fluoxetine [Prozac]: Fluoxetine [Prozac] Warnings: suicidal thoughts and behaviors;
Fluphenazine: Fluphenazine Warnings: increased mortality in elderly patients with dementia-related psychosis
Flurazepam: Flurazepam Warnings: sleepp disturbances, sever anaphylactic and anaphylactoid reactions, no evidence for pediatric use.
Flurbiprofen: Flurbiprofen Warnings: cardiovascular risk; gastrointestinal risk
Flutamide: Flutamide Warnings: hepatic injury
Fluticasone furoate / Umeclidinium / Vilanterol [Trelegy Ellipta]: Fluticasone furoate / Umeclidinium / Vilanterol [Trelegy Ellipta] Warnings: ASTHMA-RELATED DEATH
Fluticasone furoate / Vilanterol [Breo Ellipta]: Fluticasone furoate / Vilanterol [Breo Ellipta] Warnings: ASTHMA-RELATED DEATH
Fluticasone propionate / Salmeterol [Advair Diskus]]: Fluticasone propionate / Salmeterol [Advair Diskus]] Warnings: ASTHMA-RELATED DEATH
Fluticasone propionate/ Salmeterol [Airduo Respiclick]: Airduo Respiclick Warnings: asthma-related death
Fluvoxamine [Luvox]: Fluvoxamine [Luvox] Warnings: suicidality and antidepressant drugs
Fondaparinux [Arixtra]: Fondaparinux [Arixtra] Warnings: spinal/epidural hematomas
Formoterol / Glycopyrronium [Bevespi]: Formoterol / Glycopyrronium [Bevespi] Warnings: ASTHMA-RELATED DEATH
Formoterol / Mometasone [Dulera]: Formoterol / Mometasone [Dulera] Warnings: ASTHMA-RELATED DEATH
Formoterol [Foradil]: Formoterol [Foradil] Warnings: ASTHMA-RELATED DEATH
Foscarnet [Foscavir]: Foscarnet [Foscavir] Warnings: renal impairment is the major toxicity of foscavir; seizures, related to alterations in plasma minerals and electrolytes
Fosinopril: Fosinopril Warnings: fetal toxicity
Fosphenytoin [Cerebyx]: Fosphenytoin [Cerebyx] Warnings: cardiovascular risk associated with rapid infusion rates
Furosemide: Furosemide Warnings: Furosemide is a potent diuretic which, if given in excessive amounts, can lead to a profound diuresis with water and electrolyte depletion. Therefore, careful medical supervision is required and dose schedule must be adjusted to the individual patient’s needs.
Gadobenic acid [MultiHance]: Gadobenic acid [MultiHance] Warnings: NEPHROGENIC SYSTEMIC FIBROSIS
Gadobutrol [Gadavist]: Gadobutrol [Gadavist] Warnings: NEPHROGENIC SYSTEMIC FIBROSIS
Gadodiamide [Omniscan]: Gadodiamide [Omniscan] Warnings: NOT FOR INTRATHECAL USE and NEPHROGENIC SYSTEMIC FIBROSIS
Gadofosveset [Vasovist]: Gadofosveset [Vasovist] Warnings: NEPHROGENIC SYSTEMIC FIBROSIS
Gadofosveset trisodium [Ablavar]: Ablavar Warnings: nephrogenic systemic fibrosis (nsf)
Gadopentetate dimeglumine [Magnevist]: Gadopentetate dimeglumine [Magnevist] Warnings: NEPHROGENIC SYSTEMIC FIBROSIS
Gadoteric acid [Dotarem]: Gadoteric acid [Dotarem] Warnings: NEPHROGENIC SYSTEMIC FIBROSIS
Gadoteridol [ProHance]: Gadoteridol [ProHance] Warnings: NEPHROGENIC SYSTEMIC FIBROSIS
Gadoversetamide [OptiMARK]: Gadoversetamide [OptiMARK] Warnings: NEPHROGENIC SYSTEMIC FIBROSIS
Gadoxetic acid [Eovist]: Gadoxetic acid [Eovist] Warnings: NEPHROGENIC SYSTEMIC FIBROSIS
Ganciclovir [Cytovene]: Ganciclovir [Cytovene] Warnings: HEMATOLOGIC TOXICITY, IMPAIRMENT OF FERTILITY, FETAL TOXICITY, MUTAGENESIS AND CARCINOGENESIS
Gemifloxacin [Factive]: Gemifloxacin [Factive] Warnings: fluoroquinolones are associated with an increased risk of tendinitis and tendon rupture in all ages.
Gemtuzumab [Mylotarg]: Gemtuzumab [Mylotarg] Warnings: HEPATOTOXICITY
Gentamicin: Gentamicin Warnings: patients treated with aminoglycosides should be under close clinical observation because of the potential toxicity associated with their use.
Glecaprevir/Pibrentasvir [Mavyret]: Glecaprevir/Pibrentasvir [Mavyret] Risk of Hepatitis B Virus Reactivation in Patients Coninfectd with HCV and HBV
Glimepiride / Pioglitazone [Duetact]: Glimepiride / Pioglitazone [Duetact] Warnings: CONGESTIVE HEART FAILURE
Glimepiride / Rosiglitazone [Avandaryl]: Glimepiride / Rosiglitazone [Avandaryl] Warnings: CONGESTIVE HEART FAILURE
Glycopyrronium / Indacaterol [Utibron]: Glycopyrronium / Indacaterol [Utibron] Warnings: asthma-related death
Golimumab [Simponi Aria]: Golimumab [Simponi Aria] Warnings: serious infections and malignancy
Golimumab [Simponi]: Golimumab [Simponi] Warnings: serious infections and malignancy
Guaifenesin / Hydrocodone [Flowtuss]: Guaifenesin / Hydrocodone Warnings: risks from concomitant use with benzodiazepines or other cns depressants
Guaifenesin / Hydrocodone [Obredon]: Guaifenesin / Hydrocodone Warnings: risks from concomitant use with benzodiazepines or other cns depressants
Guaifenesin / Hydrocodone / Pseuoephedrine [Hycofenix]: Hycofenix Warnings: risks from concomitant use with benzodiazepines or other cns depressants
Guaifenesin / Hydrocodone [Obredon]: Guaifenesin / Hydrocodone [Obredon] Warnings: risks from concomitant use with benzodiazepines or other cns depressants
Haloperidol: Haloperidol Warnings: increased mortality in elderly patients with dementia-related psychosis
Hemin [Panhematin]: Hemin [Panhematin] Warnings: panhematin (hemin for injection) should only be used by physicians experienced in the management of porphyrias in hospitals where the recommended clinical and laboratory diagnostic and monitoring techniques are available.
House dust mite allergen extract [Odactra]: House dust mite allergen extract [Odactra] Warnings: SEVERE ALLERGIC REACTIONS
Human Serum Albumin [Optison]: Human Serum Albumin [Optison] Warnings: SERIOUS CARDIOPULMONARY REACTIONS
Human Thrombin [Evithrom]: Human Thrombin [Evithrom] Warnings: thrombosis, transmission of infectious agents
Hyaluronidase / Immune Globulin Human [Hyqvia 5 G / 50 Ml Kit]: Hyaluronidase / Immune Globulin Human [Hyqvia 5 G / 50 Ml Kit] Warnings: thrombosis
Hyaluronidase / Rituximab [Rituxan Hycela]: Hyaluronidase / Rituximab [Rituxan Hycela] Fatal Infusion Reaction; Mucocutaneous Reactions; Progressive Multifocal Leukoencephalopathy; Hep b Reactivation
Hydralazine / Hydrochlorothiazide: Hydralazine / Hydrochlorothiazide Warnings: In a few patients hydralazine may produce a clinical picture simulating systemic lupus erythematosus including glomerulonephritis.
Hydrochlorothiazide / Irbesartan [Avalide]: Hydrochlorothiazide / Irbesartan [Avalide] Warnings: fetal toxicity
Hydrochlorothiazide / Methyldopa: Hydrochlorothiazide / Methyldopa Warnings: This fixed combination drug is not indicated for initial therapy of hypertension.
Hydrochlorothiazide / Spironolactone [Aldactazide]: Hydrochlorothiazide / Spironolactone [Aldactazide] Warnings: Spironolactone, an ingredient of ALDACTAZIDE, has been shown to be a tumorigen in chronic toxicity studies in rats.
Hydrochlorothiazide / Valsartan [Diovan Hct]: Hydrochlorothiazide / Valsartan [Diovan Hct] Warnings: fetal toxicity
Hydrocodone / Ibuprofen [Vicoprofen]: Hydrocodone / Ibuprofen [Vicoprofen] Warnings: addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; cytochrome p450 3a4 interaction; risks from concomitant use with benzodiazepines or other cns depressants; and serious cardiovascular and gastrointestinal events
Hydrocodone / Pseudoephedrine [Rezira]: Hydrocodone / Pseudoephedrine [Rezira] Warnings: risks from concomitant use with benzodiazepines or other cns depressants
Hydrocodone [Hysingla ER]: Hydrocodone [Hysingla ER] Warnings: addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; cytochrome p450 3a4 interaction; and risks from concomitant use with benzodiazepines or other cns depressants
Hydrocodone [Zohydro]: Hydrocodone [Zohydro] Warnings: addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; cytochrome p450 3a4 interaction; and risks from concomitant use with benzodiazepines or other cns depressants
Hydrocodone bitartrate [Vantrela ER]: Hydrocodone bitartrate [Vantrela ER] Warnings: addiction, abuse, and misuse; life threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; cytochrome p450 3a4 interaction; and risks from concomitant use with benzodiazepines or other cns depressants.
Hydromorphone [Dilaudid]: Hydromorphone [Dilaudid] Warnings: risk of medication errors; addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; risks from concomitant use with benzodiazepines or other cns depressants
Hydromorphone [Exalgo]: Hydromorphone [Exalgo] Warnings: risk of medication errors; addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; risks from concomitant use with benzodiazepines or other cns depressants
Hydromorphone [Palladone]: Hydromorphone [Palladone] Warnings: risk of medication errors; addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; risks from concomitant use with benzodiazepines or other cns depressants
Hydromorphone Injection [Dilaudid-HP]: Hydromorphone Injection [Dilaudid-HP] Warnings: risk of medication errors; addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; risks from concomitant use with benzodiazepines or other cns depressants
Hydroxychloroquine [Plaquenil]: Hydroxychloroquine [Plaquenil] Warnings: resistant strains of malaria; ocular; cardiac effects, including cardiomyopathy and qt prolongation; worsening of psoriasis and porphyria; proximal myopathy and warnings: neuropathy; neuropsychiatric events, including suicidality; hypoglycemia.
Hydroxyethyl Starch: Hydroxyethyl Starch Warning:mortality renal replacement therapy
Hydroxyethyl Starch Solutions [Hespan]: Hydroxyethyl Starch Solutions [Hespan] Warning:mortality renal replacement therapy
Hydroxyurea [Droxia]: Hydroxyurea [Droxia] warnings: myelosuppression; malignancies; embryo-fetal toxicity; vasculitic toxicities; live vaccinations; risks with concomitant use of antiretroviral drugs;radiation recall; macrocytosis
Hydroxyurea [Siklos]: Hydroxyurea [Siklos] Warnings: prior to initiation of therapy
Ibritumomab Tiuxetan [Zevalin]: Ibritumomab Tiuxetan [Zevalin] Warnings: serious infusion reactions, prolonged and severe cytopenias, and severe cutaneous and mucocutaneous reactions.
Ibuprofen: Ibuprofen Warning:allergy alert: ibuprofen may cause a severe allergic reaction, especially in people allergic to aspirin; stomach bleeding warning; this product contains an nsaid, which may cause severe stomach bleeding.
Ibuprofen / Oxycodone [Combunox]: Ibuprofen / Oxycodone [Combunox] Warnings: addiction, abuse, and misuse? life­threatening respiratory depression? accidental ingestion? neonatal opioid withdrawal syndrome? cytochrome p450 3a4 interaction? risks from concomitant use with benzodiazepines or other cns depressants? and serious cardiovascular and gastrointestinal events.
Ibuprofen injectable [Caldolor]: Ibuprofen injectable [Caldolor] Warnings: risk of serious cardiovascular and gastrointestinal events.
Ibutilide: Ibutilide warnings: proarrhythmial
Ibutilide Fumarate [Corvert]: Ibutilide Fumarate [Corvert] Warnings: CORVERT can cause potentially fatal arrhythmias, particularly sustained polymorphic ventricular tachycardia, usually in association with QT prolongation (torsades de pointes), but sometimes without documented QT prolongation.
Idarubicin [Idamycin PFS]: Idarubicin [Idamycin PFS] Warnings: 1. Idarubicin hydrochlorideinjection should be given slowly into a freely flowing intravenous infusion. 2. As is the case with other anthracyclines the use of idarubicin hydrochloridecan cause myocardial toxicity leading to congestive heart failure. 3. As is usual with antileukemic agents, severe myelosuppression occurs when idarubicin hydrochloride is used at effective therapeutic doses. 4. It is recommended that idarubicin hydrochloride be administered only under the supervision of a physician who is experienced in leukemia chemotherapy and in facilities with laboratory and supportive resources adequate to monitor drug tolerance and protect and maintain a patient compromised by drug toxicity. 5. Dosage should be reduced in patients with impaired hepatic or renal function.
Idelalisib: Idelalisib Warnings: fatal and serious toxicities: hepatic, severe diarrhea, colitis, pneumonitis, infections, and intestinal perforation
Idelalisib [Zydelig]: Idelalisib [Zydelig] Warnings: fatal and serious toxicities: hepatic, severe diarrhea, colitis, pneumonitis, infections, and intestinal perforation.
Idursulfase [Elaprase]: Idursulfase [Elaprase] Warnings: risk of anaphylaxis
Ifosfamide [Ifex]: Ifosfamide [Ifex] Warnings: myelosuppression, neurotoxicity, and urotoxicity
Iloperidone [Fanapt]: Iloperidone [Fanapt] Warnings: increased mortality in elderly patients with dementia-related psychosis
Imipramine: Imipramine Warnings: suicidality and antidepressant drugs
Immune Globulin Human [Gamunex]: Immune Globulin Human [Gamunex] Warnings: thrombosis, renal dysfunction, and acute renal failure
Immune Globulin Human [Winrho]: Immune Globulin Human [Winrho] Warnings: intravascular hemolysis (ivh) in immune thrombocytopenic purpura (itp).
Indacaterol [Arcapta Neohaler]: Indacaterol [Arcapta Neohaler] Warnings: asthma-related death
Indomethacin: Indomethacin Warnings: risk of serious cardiovascular and gastrointestinal events
Infliximab [Remicade]: Infliximab [Remicade] Warnings: serious infections and malignancy
Infliximab-abda [Renflexis]: Infliximab-abda [Renflexis] Warnings: serious infections and malignancy
Infliximab-dyyb [Inflectra]: Infliximab-dyyb [Inflectra] Warnings: serious infections and malignancy
Inotuzumab ozogamicin [Besponsa]: Inotuzumab ozogamicin [Besponsa] Warnings: Hepatotoxicity, Including Hepatic Veno-Occlusive Disease (VOD – also known as Sinusoidal Obstruction Syndrome) and Increased Risk of Post-Hematopoietic Stem Cell Transplant (HSCT) Non-Relapse Mortality.
Insulin Degludec / Liraglutide [Xultophy]: Insulin Degludec / Liraglutide [Xultophy] Warnings: risk of thyroid c-cell tumors
Insulin Human [Afrezza]: Insulin Human [Afrezza] Warnings: RISK OF ACUTE BRONCHOSPASM IN PATIENTS WITH CHRONIC LUNG DISEASE
Interferon Alfa-2b: Interferon Alfa-2b Warnings: alpha interferons, including intron a, cause or aggravate fatal or life-threatening neuropsychiatric, autoimmune, ischemic, and infectious disorders.
Interferon alfacon-1 Injection [Infergen]: Interferon alfacon-1 Injection [Infergen] Warnings: FATAL OR LIFE-THREATENING DISORDERS AND RIBAVIRIN ASSOCIATED EFFECTS
Iodixanol [Visipaque]: Iodixanol [Visipaque] Warnings: NOT FOR INTRATHECAL USE
Iohexol [Omnipaque]: Iohexol [Omnipaque] Warnings: NOT FOR INTRATHECAL USE
Iopamidol [Isovue]: Iopamidol [Isovue] Warnings: NOT FOR INTRATHECAL USE
Iopromide [Ultravist]: Iopromide [Ultravist] Warnings: NOT FOR INTRATHECAL USE
Ioversol [Optiray]: Ioversol [Optiray] Warnings: NOT FOR INTRATHECAL USE
Ipilimumab [Yervoy]: Ipilimumab [Yervoy] Warnings: immune-mediated adverse reactions
Irbesartan [Avapro]: Irbesartan [Avapro] Warnings: fetal toxicity
Irinotecan [Camptosar]: Irinotecan [Camptosar] Warnings: diarrhea and myelosuppression
Irinotecan Liposome [Onivyde]: Irinotecan Liposome [Onivyde] Warning: Severe neutropenia and severe diarrhea
Iron Carbonyl – Iron containing vitamins / products: Iron Carbonyl – Iron containing vitamins / products Warnings: accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6 years of age.
Iron Dextran [Dexferrum]: Iron Dextran [Dexferrum] Warnings: risk for anaphylactic-type reactions
Iron Dextran [Infed]: Iron Dextran [Infed] Warnings: risk for anaphylactic-type reactions
Isocarboxazid [Marplan]: Isocarboxazid [Marplan] Warnings: suicidality and antidepressant drugs
Isoniazid / Pyrazinamide / Rifampicin [Rifater]: Isoniazid / Pyrazinamide / Rifampicin [Rifater] Warnings: severe and sometimes fatal hepatitis associated with isoniazid therapy has been reported and may occur or may develop even after many months of treatment.
Isoniazid / Rifampicin [Rifamate]: Isoniazid / Rifampicin [Rifamate] Warnings: severe and sometimes fatal hepatitis associated with isoniazid therapy has been reported and may occur or may develop even after many months of treatment.
Isotretinoin [Absorica]: Isotretinoin [Absorica] Warnings: causes birth defects
Itraconazole [Sporanox]: Itraconazole [Sporanox] Warnings: congestive heart failure, cardiac effects and drug interactions
Ixabepilone [Ixempra]: Ixabepilone [Ixempra] Warnings: toxicity in hepatic impairment
Ketamine [Ketalar]: Ketamine [Ketalar] Warnings: cardiac function should be continually monitored during the procedure in patients found to have hypertension or cardiac decompensation; postoperative confusional; respiratory depression; pediatric neurotoxicity
Ketoconazole [Nizoral]: Ketoconazole [Nizoral] Warnings: hepatotoxicity; qt prolongation and drug interactions leading to qt prolongation
Ketoprofen: Ketoprofen Warnings: cardiovascular thrombotic events; gastrointestinal risk
Ketorolac: Ketorolac Warnings: gastrointestinal risk; cardiovascular risk; renal risk; risk of bleeding; hypersensitivity; intrathecal or epidural administration; risk during labor and delivery; concomitant use with nsaids; special populations
Ketorolac Nasal Spray [Sprix]: Ketorolac Nasal Spray [Sprix] Warnings: risk of serious cardiovascular and gastrointestinal events
Lamivudine / Raltegravir [Dutrebis]: Lamivudine / Raltegravir [Dutrebis] Warnings: lactic acidosis/severe hepatomegaly and post-treatment exacerbations of hepatitis b in coinfected patients.
Lamivudine / Zidovudine [Combivir]: Lamivudine / Zidovudine [Combivir Warnings: hematologic toxicity, myopathy, lactic acidosis and severe hepatomegaly with steatosis, and exacerbations of hepatitis b.
Lamivudine [Epivir Hbv]: Lamivudine [Epivir Hbv] Warnings: risk of lactic acidosis, exacerbations of hepatitis b upon discontinuation of epivir-hbv, and risk of hiv-1 resistance if epivir-hbv is used in patients with unrecognized or untreated hiv-1 infection.
Lamivudine [Epivir]: Lamivudine [Epivir] Warnings: risk of lactic acidosis, exacerbations of hepatitis b upon discontinuation of epivir-hbv, and risk of hiv-1 resistance if epivir-hbv is used in patients with unrecognized or untreated hiv-1 infection.
Lamotrigine [Lamictal ODT]: Lamotrigine [Lamictal ODT] Warnings: serious skin rashes
Lamotrigine [Lamictal XR]: Lamotrigine [Lamictal XR] Warnings: serious skin rashes
Lapatinib [Tykerb]: Lapatinib [Tykerb] Warnings: hepatotoxicity
Laronidase [Aldurazyme]: Laronidase [Aldurazyme] Warnings: risk of anaphylaxis
Ledipasvir / Sofosbuvir [Harvoni]: Ledipasvir / Sofosbuvir [Harvoni] Warnings: risk of hepatitis b virus reactivation in patients coinfected with hcv and hbv
Leflunomide [Arava]: Leflunomide [Arava] Warnings: embryo-fetal toxicity and hepatotoxicity
Lenalidomide [Revlimid]: Lenalidomide [Revlimid] Warnings: embryo-fetal toxicity, hematologic toxicity, and venous and arterial thromboembolism
Lesinurad [Zurampic]: Lesinurad [Zurampic] Warnings: risk of acute renal failure, more common when used without a xanthine oxidase inhibitor
Levofloxacin [Levaquin]: Levofloxacin [Levaquin] Warnings: serious adverse reactions including tendinitis, tendon rupture, peripheral neuropathy, central nervous system effects and exacerbation of myasthenia gravis
Levomilnacipran [Fetzima]: Levomilnacipran [Fetzima] Warnings: suicidal thoughts and behaviors
Levonorgestrel: Levonorgestrel warnings: allergy alert: do not use if you have ever had an allergic reaction to levonorgestrel; sexually transmitted disease (stds) alert; this product does not protect against hiv/aids or other stds.
Levothyroxine: Levothyroxine warnings: keep out of reach of children. In case of overdose, contact physician or a poison control center right away; if pregnant or breast-feeding, ask a health professional before use.
Lidocaine viscous 2%: Lidocaine viscous 2% Warnings: Life-threatening and fatal events in infants and young children
Linaclotide [Linzess]: Linaclotide [Linzess] Warnings: risk of serious dehydration in pediatric patients
Lincomycin [Lincocin]: Lincomycin [Lincocin] Warnings: clostridium difficile associated diarrhea (cdad) has been reported with use of nearly all antibacterial agents, including lincomycin and may range in severity from mild diarrhea to fatal colitis.
Lindane: Lindane warnings: lindane lotion should only be used in patients who cannot tolerate or have failed first-line treatment with safer medications for the treatment of scabies; Neurologic toxicity.
Liothyronine [Cytomel]: Liothyronine [Cytomel] warnings: drugs with thyroid hormone activity, alone or together with other therapeutic agents, have been used for the treatment of obesity. In euthyroid patients, doses within the range of daily hormonal requirements are ineffective for weight reduction. Larger doses may produce serious or even life threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects.
lipid injectable emulsion [Smoflipid]: lipid injectable emulsion [Smoflipid] Warnings: DEATH IN PRETERM INFANTS
Liraglutide [Saxenda]: Liraglutide [Saxenda] Warnings: risk of thyroid c-cell tumors
Liraglutide [Victoza]: Liraglutide [Victoza] Warnings: risk of thyroid c-cell tumors
Lisdexamfetamine [Vyvanse]: Lisdexamfetamine [Vyvanse] Warnings: abuse and dependence
Lisinopril: Lisinopril Warnings: Anaphylactoid and Possibly Related Reactions; Angioedma.
Lithium [Lithobid]: Lithium [Lithobid] Warnings: lithium toxicity is closely related to serum lithium levels, and can occur at doses close to therapeutic levels. Facilities for prompt and accurate serum lithium determinations should be available before initiating therapy.
Lomitapide [Juxtapid]: Lomitapide [Juxtapid] Warnings: risk of hepatotoxicity
Lomustine [CeeNU]: Lomustine [CeeNU] Warnings: CeeNU (lomustine) should be administered under the supervision of a qualified physician experienced in the use of cancer chemotherapeutic agents.
Lorazepam [Ativan]: Lorazepam [Ativan] Warnings: Risk From Concomitant Use With Opioids
Losartan: Losartan Warnings: fetal toxicity
Loxapine [Adasuve]: Loxapine [Adasuve] Warnings: bronchospasm; increased mortality in elderly patients with dementia-related psychosis
Lurasidone [Latuda]: Lurasidone [Latuda] Warnings: increased mortality in elderly patients with dementia-related psychosis
Macitentan [Opsumit]: Macitentan [Opsumit] Warnings: embryo-fetal toxicity
Maprotiline: Maprotiline Warnings: suicidality and antidepressant drugs
Maraviroc [Selzentry]: Maraviroc [Selzentry] Warnings: hepatotoxicity
Mechlorethamine [Mustargen]: Mechlorethamine [Mustargen] Warnings: mechlorethamine HCl) should be administered only under the supervision of a physician who is experienced in the use of cancer chemotherapeutic agents.
Medroxyprogesterone [Depo-Provera Contraceptive Injection]: Medroxyprogesterone [Depo-Provera Contraceptive Injection] Warnings: lthromboembolic disorders; ocular disorders, multi-dose use.
Mefenamic acid: Mefenamic acid Warnings: risk of serious cardiovascular and gastrointestinal events
Mefloquine [Lariam]: Mefloquine [Lariam] Warnings: mefloquine may cause neuropsychiatric adverse reactions that can persist after mefloquine has been discontinued. Mefloquine should not be prescribed for prophylaxis in patients with major psychiatric disorders. During prophylactic use, if psychiatric or neurologic symptoms occur, the drug should be discontinued and an alternative medication should be substituted.
Meloxicam [Vivlodex]: Meloxicam [Vivlodex] Warnings: cardiovascular risk; gastrointestinal risk
Melphalan [Alkeran]: Melphalan [Alkeran] Warnings: melphalan tablets usp should be administered under the supervision of a qualified physician experienced in the use of cancer chemotherapeutic agents. Severe bone marrow suppression with resulting infection or bleeding may occur. Melphalan is leukemogenic in humans. Melphalan produces chromosomal aberrations in vitro and in vivo and, therefore, should be considered potentially mutagenic in humans.
Meperidine [Demerol]: Meperidine [Demerol] Addiction, Abuse, and Misuse; Life -Threatening Respiratory Depression; Neonatal Opioid Withdrawal Syndrome; Cytochrome P450 3A4 interaction; Risks from Concomitant Use with Benzodiazepines or Other CNS Depressants; and Monoamine Oxidase (MOA) Inhibitors Interactions
Mercaptopurine: Mercaptopurine warnings: mercaptopurine is mutagenic in animals and humans, carcinogenic in animals, and may increase the patient’s risk of neoplasia; bone marrow toxicity; hepatotoxicity.
Metformin: Metformin lactic acidosis
Metformin / Pioglitazone [Actoplus Met XR]: Metformin / Pioglitazone [Actoplus Met XR] Warnings: CONGESTIVE HEART FAILURE AND LACTIC ACIDOSIS
Metformin / Pioglitazone [Actoplus Met]: Metformin / Pioglitazone [Actoplus Met] Warnings: CONGESTIVE HEART FAILURE AND LACTIC ACIDOSIS
Metformin / Rosiglitazone [Avandamet]: Metformin / Rosiglitazone [Avandamet] Warnings: CONGESTIVE HEART FAILURE AND LACTIC ACIDOSIS
Metformin [Glucophage]: Metformin [Glucophage] Warnings: lactic acidosis
Methadone [Dolophine]: Methadone [Dolophine] Warnings: addiction, abuse, and misuse; lifethreatening respiratory depression; accidental ingestion; life-threatening qt prolongation; neonatal opioid withdrawal syndrome; interactions with drugs affecting cytochrome p450 isoenzymes; risks from concomitant use with benzodiazepines or other cns depressants; and treatment for opioid addiction.
Methadone Injection: Methadone Injection Warnings: addiction, abuse, and misuse; life-threatening respiratory depression; life-threatening qt prolongation; neonatal opioid withdrawal syndrome; interactions with drugs affecting cytochrome p450 isoenzymes; risks from concomitant use with benzodiazepines or other cns depressants; and treatment of opioid addiction.
Methamphetamine: Methamphetamine Warnings: methamphetamine has a high potential for abuse. It should thus be tried only in weight reduction programs for patients in whom alternative therapy has been ineffective. Administration of methamphetamine for prolonged periods of time in obesity may lead to drug dependence and must be avoided. Particular attention should be paid to the possibility of subjects obtaining methamphetamine for non-therapeutic use or distribution to others, and the drug should be prescribed or dispensed sparingly. Misuse of methamphetamine may cause sudden death and serious cardiovascular adverse events.
Methohexital: Methohexital Warnings: brevital should be used only in hospital or ambulatory care settings that provide for continuous monitoring of respiratory (e.g. Pulse oximetry) and cardiac function.
Methohexital [Brevital]: Methohexital [Brevital] Warnings: should be used only in hospital or ambulatory care settings that provide for continuous monitoring of respiratory (e.g. pulse oximetry) and cardiac function. Immediate availability of resuscitative drugs and age- and size-appropriate equipment for bag/valve/mask ventilation and intubation and personnel trained in their use and skilled in airway management should be assured.
Methotrexate [Otrexup]: Methotrexate [Otrexup] Warnings: severe toxic reactions, including embryo-fetal toxicity and death
Methotrexate [Rasuvo]: Methotrexate [Rasuvo] Warnings: severe toxic reactions, including embryo-fetal toxicity and death
Methotrexate [Rheumatrex]: Methotrexate [Rheumatrex] Warnings: methotrexate should be used only by physicians whose knowledge and experience include the use of antimetabolite therapy because of the possibility of serious reactions (which can be fatal)
Methotrexate [Xatmep]: Methotrexate [Xatmep] Warnings: SEVERE TOXIC REACTIONS, INCLUDING EMBRYO FETAL TOXICITY
Methotrexate Sodium for Injection : Methotrexate Sodium for Injection Warnings: multiple severe warnings
Methoxsalen [8-MOP]: Methoxsalen [8-MOP] Warnings: should only be used by physicians who have special competence in diagnois and treatment of psoriasis and photochemotherapy.
Methoxsalen [Oxsoralen -Ultra]: Methoxsalen [Oxsoralen -Ultra] Warnings: skin burning, carcinogenicity, cataractogenicity, actinic degeneration, basal cell carcinomas, radiation therapy ….
Methoxsalen [Oxsoralen]: Methoxsalen [Oxsoralen] Methoxsalen lotion is a potent drug capable of producing severe burns if improperly used. Warnings: It should be applied only by a physician under controlled conditions for light exposure and subsequent light shielding. This preparation should never be dispensed to a patient.
Methoxsalen [Uvadex]: Methoxsalen [Uvadex] Warnings: methoxsalen should be used only by physicians who have special competence in the diagnosis and treatment of cutaneous t-cell lymphoma and who have special training and experience.
Methoxy polyethylene glycol-epoetin beta [Mircera]: Methoxy polyethylene glycol-epoetin beta [Mircera] Warnings: increase the risk of death, myocardial infarction, stroke, venous thromboembolism, thrombosis of vascular access, and tumor progression or recurrence
Methylene Blue [Provay Blue]: Methylene Blue [Provay Blue] Warnings: serotonin syndrome with concomitant use of serotonergic drugs
Methylphenidate [Aptensio XR]: Methylphenidate [Aptensio XR] Warnings: Tolerance and dependence
Methylphenidate [Cotempla XR-ODT]: Methylphenidate [Cotempla XR-ODT] Warnings: tolerance and dependence
Methylphenidate [Daytrana]: Methylphenidate [Daytrana] Warnings: Tolerance and dependence
Methylphenidate [Quillichew]: Methylphenidate [Quillichew] Warnings: Tolerance and dependence
Methylphenidate [Quillivant]: Methylphenidate [Quillivant] Warnings: Tolerance and dependence
Methylphenidate [Ritalin]: Methylphenidate [Ritalin] Warnings: dependence, serious cardiovascular events, psychiatric adverse events, long-term suppression of growth, seizures, preapism, peripheral vasculopathy, visual disturibance …
Metoclopramide [Metozolv]: Metoclopramide [Metozolv] Warnings: tardive dyskinesia
Metoclopramide [Reglan]: Metoclopramide [Reglan] Warnings: tardive dyskinesia
Metolazone [Mykrox]: Metolazone [Mykrox] warnings: rapid onset hyponatremia and/or hypokalemia
Metolazone [Zaroxolyn]: Metolazone [Zaroxolyn] warnings: rapid onset hyponatremia and/or hypokalemia
Metoprolol [Toprol]: Metoprolol [Toprol] Warnings: cardiac ischemia after abrupt discontinuation
Metreleptin [Myalept]: Metreleptin [Myalept] Warnings: risk of anti-metreleptin antibodies with neutralizing activity and risk of lymphoma
Metronidazole [Flagyl]: Metronidazole [Flagyl] Warnings: Metronidazole has been shown to be carcinogenic in mice and rats
Mexiletine: Mexiletine Warnings: mortality, accute liver failure
Midazolam [Versed]: Midazolam [Versed] Warnings: Personnel and Equipment for Monitoring and Resuscitation, risks from concomitant use with opioids
Midodrine [Proamatine]: Midodrine [Proamatine] warnings: supine hypertension
Mifepristone [Korlym]: Mifepristone [Korlym] Warnings: termination of pregnancy
Mifepristone [Mifeprex]: Mifepristone [Mifeprex] Warnings: serious and sometime fatal infections or bleeding
Milnacipran [Savella]: Milnacipran [Savella] Warnings: suicidality and antidepressant drugs
Miltefosine [Impavido]: Miltefosine [Impavido] Warnings: embryo-fetal toxicity
Minoxidil [Loniten]: Minoxidil [Loniten] warnings: for external use only, powerful antiypertensive with potential serious adverse effects, for use by men only.
Minoxidil [Rogaine]: Minoxidil [Rogaine] warnings: for external use only. For use by men only.
Mipomersen [Kynamro]: Mipomersen [Kynamro] Warnings: risk of hepatotoxicity
Mirtazapine: Mirtazapine Warnings: suicidality and antidepressant drugs
Misoprostol: Misoprostol Warnings: misoprostol administration to women who are pregnant can cause birth defects, abortion, or premature birth.
Mitomycin [Mutamycin]: Mitomycin [Mutamycin] Warnings: should be adminstered under the supervision of a qualified physician experienced in the use of cancer chemotherpeutic agents.
Mitotane [Lysodren]: Mitotane [Lysodren] Warnings: should be adminstered under the supervision of a qualified physician experienced in the use of cancer chemotherpeutic agents.
Mitoxantrone for Injection: Mitoxantrone for Injection Warnings: cardiotoxicity; multiple sclerosis patients; secondary leukemia
Modafinil [Provigil]: Modafinil [Provigil] 9999
Moexipril: Moexipril Warnings: fetal toxicity
Molindone: Molindone Warnings: increased mortality in elderly patients with dementia-related psychosis
Morphine / Naltrexone [Embeda]: Morphine / Naltrexone [Embeda] Warnings: addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; interaction with alcohol; risks with concomitant use with benzodiazepines or other cns depressants.
Morphine [Arymo ER]: Morphine [Arymo ER] Warnings: addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; interaction with alcohol; risks with concomitant use with benzodiazepines or other cns depressants.
Morphine [Avinza]: Morphine [Avinza] Warnings: addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; interaction with alcohol; risks with concomitant use with benzodiazepines or other cns depressants.
Morphine [Duramorph]: Morphine [Duramorph] Warnings: addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; interaction with alcohol; risks with concomitant use with benzodiazepines or other cns depressants.
Morphine [Kadian]: Morphine [Kadian] Warnings: addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; interaction with alcohol; risks with concomitant use with benzodiazepines or other cns depressants.
Morphine [Morphabond]: Morphine [Morphabond] Warnings: addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; interaction with alcohol; risks with concomitant use with benzodiazepines or other cns depressants.
Morphine [Ms Contin]: Morphine [Ms Contin] Warnings: addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; interaction with alcohol; risks with concomitant use with benzodiazepines or other cns depressants.
Morphine Tablets: Morphine Tablets Warnings: addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; interaction with alcohol; risks with concomitant use with benzodiazepines or other cns depressants.
Moxifloxacin [Avelox]: Moxifloxacin [Avelox] Warnings: serious adverse reactions including tendinitis, tendon rupture, peripheral neuropathy, centrial nervous system effects and exacerbation of myasthenia gravis.
Mycophenolate [CellCept]: Mycophenolate [CellCept] Warnings: EMBRYOFETAL TOXICITY, MALIGNANCIES AND SERIOUS INFECTIONS .
Mycophenolate mofetil: Mycophenolate mofetil Warnings: immunosuppression may lead to increased susceptibility to infection and possible development of lymphoma.
Mycophenolic Acid [Myfortic]: Mycophenolic Acid [Myfortic] Warnings: EMBRYOFETAL TOXICITY, MALIGNANCIES, AND SERIOUS INFECTIONS
Nabumetone: Nabumetone warnings: cardiovascular risk; gastrointestinal risk.
Nadolol: Nadolol warnings: cardiac failure; nonallergic bronchospasm (e.g., chronic bronchitis, emphysema); major surgery; diabetes and hypoglycemia; thyrotoxicosis.
Naltrexone / Oxycodone [Targiniq ER]: Naltrexone / Oxycodone [Targiniq ER] Warnings: addiction, abuse, and misuse; lifethreatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; cytochrome p450 3a4 interaction; and risks from concomitant use with benzodiazepines and other cns depressants
Naltrexone / Oxycodone [Troxyca ER]: Naltrexone / Oxycodone [Troxyca ER] Warnings: addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; cytochrome p450 3a4 interaction; and risks from concomitant use with benzodiazepines or other cns depressants.
Naproxen: Naproxen Warnings: allergy alert: naproxen sodium may cause a severe allergic reaction, especially in people allergic to aspirin.
Natalizumab [Tysabri]: Natalizumab [Tysabri] Warnings: progressive multifocal leukoencephalopathy
Nebivolol / Valsartan: Nebivolol / Valsartan Warnings: fetal toxicity
Necitumumab [Portrazza]: Necitumumab [Portrazza] Warnings: cardiopulmonary arrest and hypomagnesemia
Nefazodone: Nefazodone Warnings: suicidality and antidepressant drugs
Nelarabine [Arranon]: Nelarabine [Arranon] Warnings: neurologic adverse reactions
Neomycin Oral: Neomycin Oral Warnings: systemic absorption of neomycin occurs following oral administration and toxic reactions may occur
Nevirapine [Viramune]: Nevirapine [Viramune] Warnings: life-threatening (including fatal) hepatotoxicity and skin reactions
Nilotinib [Tasigna]: Nilotinib [Tasigna] Warnings: qt prolongation and sudden deaths
Nilutamide [Nilandron]: Nilutamide [Nilandron] warnings: interstitial pneumonitis; hepatitis; use in women.
Nimodipine: Nimodipine Warnings: do not administer nimodipine intravenously or by other parenteral routes. Deaths and serious, life threatening adverse events have occurred when the contents of nimodipine capsules have been injected parenterally
Nitroprusside Sodium [Nitropress]: Nitroprusside Sodium [Nitropress] Warnings: sodium nitroprusside injection is not suitable for direct injection. The solution must be further diluted in sterile 5% dextrose injection before infusion. Sodium nitroprusside injection can cause precipitous decreases in blood pressure. In patients not properly monitored, these decreases can lead to irreversible ischemic injuries or death.
Norepinephrine Bitartrate [Levophed]: Norepinephrine Bitartrate [Levophed] Warnings: LEVOPHED should be used with extreme caution in patients receiving monoamine oxidase inhibitors (MAOI) or antidepressants of the triptyline or imipramine types, because severe, prolonged hypertension may result.
Nortriptyline: Nortriptyline Warnings: suicidality and antidepressant drugs
Obiltoxaximab: Obiltoxaximab Warnings: hypersensitivity and anaphylaxis
Obiltoxaximab [Anthim]: Obiltoxaximab [Anthim] Warnings: hypersensitivity and anaphylaxis
Obinutuzumab [Gazyva]: Obinutuzumab [Gazyva] Warnings: hypersensitivity and anaphylaxis
Ofatumumab [Arzerra]: Ofatumumab [Arzerra] Warnings: hepatitis b virus (hbv) reactivation and progressive multifocal leukoencephalopathy
Ofloxacin: Ofloxacin Warnings: fluoroquinolones are associated with an increased risk of tendinitis and tendon rupture in all ages.
Olanzapine [Zyprexa]: Olanzapine [Zyprexa] Warnings: increased mortality in elderly patients with dementia-related psychosis
Olanzapine ER injection [Zyprexa Relprevv]: Olanzapine ER injection [Zyprexa Relprevv] Warnings: increased mortality in elderly patients with dementia-related psychosis
Olmesartan: Olmesartan Warnings: fetal toxicity
Olodaterol / Tiotropium [Stiolto Respimat]: Olodaterol / Tiotropium [Stiolto Respimat] Warnings: asthma-related death
Olodaterol [Striverdi Respimat]: Olodaterol [Striverdi Respimat] Warnings: asthma-related death
Omalizumab [Xolair]: Omalizumab [Xolair] Warnings: anaphylaxis
Ombitasvir / Paritaprevir / Ritonavir [Technivie]: Ombitasvir / Paritaprevir / Ritonavir [Technivie] Warnings: RISK OF HEPATITIS B VIRUS REACTIVATION IN PATIENTS COINFECTED WITH HCV AND HBV
Ospemifene [Osphena]: Ospemifene [Osphena] Warnings: endometrial cancer and cardiovascular disorders
Oxaliplatin [Eloxatin]: Oxaliplatin [Eloxatin] Warnings: anaphylactic reactions
Oxandrolone: Oxandrolone Warnings: peliosis hepatis, a condition in which liver and sometimes splenic tissue is replaced with blood-filled cysts, has been reported in patients receiving androgenic anabolic steroid therapy.
Oxaprozin: Oxaprozin Warnings: cardiovascular risk; gastrointestinal risk
Oxazepam: Oxazepam Risk From Concomitant Use With Opioids
Oxycodone [Oxaydo]: Oxycodone [Oxaydo] Warnings: addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; cytochrome p450 3a4 interaction; and risks from concomitant use with benzodiazepines or other cns depressants.
Oxycodone [Oxycontin]: Oxycodone [Oxycontin] Warnings: addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; cytochrome p450 3a4 interaction; and risks from concomitant use with benzodiazepines or other cns depressants.
Oxycodone [Roxicodone]: Oxycodone [Roxicodone] Warnings: addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; cytochrome p450 3a4 interaction; and risks from concomitant use with benzodiazepines or other cns depressants.
Oxycodone [Roxybond]: Oxycodone [Roxybond] Warnings: addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; cytochrome p450 3a4 interaction; and risks from concomitant use with benzodiazepines or other cns depressants.
Oxycodone [Xtampza]: Oxycodone [Xtampza] Warnings: addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; cytochrome p450 3a4 interaction; and risks from concomitant use with benzodiazepines or other cns depressants.
Oxycodone Oral Solution: Oxycodone Oral Solution Warnings: addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; cytochrome p450 3a4 interaction; and risks from concomitant use with benzodiazepines or other cns depressants.
Oxymetholone [Anadrol-50]: Oxymetholone [Anadrol-50] Warnings: the following conditions have been reported in patients receiving androgenic anabolic steroids as a general class of drugs: peliosis hepatitis, liver cell tumors, blood lipid changes
Oxymorphone [Opana ER]: Oxymorphone [Opana ER] Warnings: addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; interaction with alcohol; and risks from concomitant use with benzodiazepines or other cns depressants
Oxytocin [Pitocin]: Oxytocin [Pitocin] Warnings: administered only by the intravenous route and with adequate medical supervision.
Paclitaxel: Paclitaxel Warnings: Paclitaxel should be administered under the supervision of a physician experienced in the use of cancer chemotherapeutic agents.
Paclitaxel [Abraxane]: Paclitaxel [Abraxane] Warnings: NEUTROPENIA
Paliperidone: Paliperidone Warnings: increased mortality in elderly patients with dementia-related psychosis
Pancuronium: Pancuronium Warnings: pancuronium bromide injection, usp should be administered in carefully adjusted doses by or under the supervision of experienced clinicians who are familiar with its actions and the possible complications that might occur following its use.
Panitumumab [Vectibix]: Panitumumab [Vectibix] Warnings: dermatologic toxicity
Panobinostat [Farydak]: Panobinostat [Farydak] Warnings: fatal and serious toxicities: severe diarrhea and cardiac toxicities
Parathyroid hormone [Natpara]: Parathyroid hormone [Natpara] Warnings: potential risk of osteosarcoma
Paroxetine [Brisdelle]: Paroxetine [Brisdelle] Warnings: SUICIDAL THOUGHTS AND BEHAVIORS
Patiromer: Patiromer Warnings: worsening of gastrointestinal motility; hypomagnesemia.
Pazopanib [Votrient]: Pazopanib [Votrient] Warnings: hepatotoxicity
Peginesatide [Omontys]: Peginesatide [Omontys] Warnings: esas increase the risk of death, myocardial infarction, stroke, venous thromboembolism, thrombosis of vascular access and tumor progression or recurrence.
Peginterferon Alfa-2a [Pegasys]: Peginterferon Alfa-2a [Pegasys] Warnings: risk of serious disorders
Peginterferon alfa-2b [Pegintron]: Peginterferon alfa-2b [Pegintron] Warnings: RISK OF SERIOUS DISORDERS AND RIBAVIRIN ASSOCIATED EFFECTS.
Peginterferon beta-1a: Peginterferon beta-1a Warnings: RISK OF SERIOUS DISORDERS AND RIBAVIRIN-ASSOCIATED EFFECTS
Pegloticase [Krystexxa]: Pegloticase [Krystexxa] Warnings: RISK OF SERIOUS DISORDERS AND RIBAVIRIN ASSOCIATED EFFECTS.
Penicillamine [Cuprimine]: Penicillamine [Cuprimine] Warnings: physicians planning to use should thoroughly familiarize themselves with its toxicity, special dosage considerations, and therapeutic benefits.
Penicillin G benzathine/penicillin G procaine [Bicillin C-R]: Penicillin G benzathine/penicillin G procaine [Bicillin C-R] Warnings: NOT FOR INTRAVENOUS USE.
Pentazocine [Talwin]: Pentazocine [Talwin] Warnings: ADDICTION, ABUSE, AND MISUSE; LIFE-THREATENING RESPIRATORY DEPRESSION; NEONATAL OPIOID WITHDRAWAL SYNDROME; AND RISKS FROM CONCOMITANT USE WITH BENZODIAZEPINES OR OTHER CNS DEPRESSANTS
Pentostatin [Nipent]: Pentostatin [Nipent] Warnings: should be administered under the supervision of a physician qualified and experienced in the use of cancer chemotherapeutic agents.
Perampanel [Fycompa]: Perampanel [Fycompa] Warnings: serious psychiatric and behavioral reactions
Perflutren [Definity]: Perflutren [Definity] Warnings: SERIOUS CARDIOPULMONARY REACTIONS
Perphenazine: Perphenazine Warnings: increased mortality in elderly patients with dementia-related psychosis
Pertuzumab [Perjeta]: Pertuzumab [Perjeta] Warnings: left ventricular dysfunction and embryo-fetal toxicity
Phenelzine: Phenelzine Warnings: suicidality and antidepressant drugs
Phentermine / Topiramate: Phentermine / Topiramate Warnings: federally controlled substance (civ) because it contains phentermine and can be abused or lead to drug dependence.
Phentermine [Adipex-P]: Phentermine [Adipex-P] Warnings: Coadministration with other drugs for weight loss is note recommended; rare cases of primary pulmonary hypetension.
Phenylephrine Injection [Neo-Synephrine]: Phenylephrine Injection [Neo-Synephrine] Warnings: exacerbation of angina, hear failure, or pulmonary arterial hypertension; bradycardia, risk with autonmic dysufnciton; skin and subcutaneous necrosis, pressor effect with concomitan oxytocic drugs,; allergic reaction; peripheral and visceral ischemia; renal toxicity.
Phenytoin Injection [Dilantin]: Phenytoin Injection [Dilantin] Warnings: CARDIOVASCULAR RISK ASSOCIATED WITH RAPID INFUSION
Phytonadione Injection [AquaMephyton]: Phytonadione Injection [AquaMephyton] WARNING – INTRAVENOUS AND INTRAMUSCULAR USE
Pimavanserin [Nuplazid]: Pimavanserin [Nuplazid] Warnings: increased mortality in elderly patients with dementia-related psychosis
Pimecrolimus Cream [Elidel]: Pimecrolimus Cream [Elidel] Warnings: long-term safety of topical calcineurin inhibitors has not been established
Pimozide: Pimozide Warnings: tardive dyskinesia; neuroleptic malignant syndrome (nms); Sudden, unexpected deaths
Pioglitazone [Actos]: Pioglitazone [Actos] Warnings: congestive heart failure
Piroxicam: Piroxicam Warnings: cardiovascular risk; gastrointestinal risk
Plecanatide [Trulance]: Plecanatide [Trulance] Warnings: RISK OF SERIOUS DEHYDRATION IN PEDIATRIC PATIENTS.
Polymyxin B Injection: Polymyxin B Injection Warnings: caution: when this drug is given intramuscularly and/or intrathecally, it should be given only to hospitalized patients, so as to provide constant su-pervision by a physician.
Polysaccharide Iron Complex [Niferex]: Polysaccharide Iron Complex [Niferex] WARNING: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. KEEP THIS PRODUCT OUT OF REACH OF CHILDREN. In case of accidental overdose, call a doctor or poison control center immediately.
Pomalidomide [Pomalyst]: Pomalidomide [Pomalyst] Warnings: embryo-fetal toxicity and venous and arterial thromboembolism
Ponatinib [Iclusig]: Ponatinib [Iclusig] Warnings: arterial occlusion, venous thromboembolism, heart failure, and hepatotoxicity
Pramlintide [Symlin]: Pramlintide [Symlin] Warnings: severe hypoglycemia
Prasugrel [Effient]: Prasugrel [Effient] Warnings: bleeding risk
Primaquine: Primaquine Warnings: physicians should completely familiarize themselves with the complete contents of this leaflet before prescribing.
Procainamide: Procainamide Warnings: prolonged administration often leads to the development of a positive anti-nuclear antibody (ana) test, with or without symptoms of a lupus erythematosus-like syndrome.
Procarbazine [Matulane]: Procarbazine [Matulane] Warnings: it is recommended to be given only by or under the supervision of a physician experienced in the use of potent antineoplastic drugs.
Prochlorperazine: Prochlorperazine Warnings: increased mortality in elderly patients with dementia-related psychosis
Progesterone [Prometrium]: Progesterone [Prometrium] Warnings: cardiovascular disorders, breast cancer and probable dementia for estrogen plus progestin therapy
Promethazine: Promethazine Warnings: promethazine hydrochloride should not be used in pediatric patients less than 2 years of age because of the potential for fatal respiratory depression.
Propafenone [Rythmol SR]: Propafenone [Rythmol SR] Warnings: mortality
Propranolol: warnings: angina pectoris; hyper sensitivity and skins reactions; cardiac failure; nonallergic bronschospasm; major surgery, diabetes and hypoglycemia; thyrotoxicosis; wolff-parkinson-white syndrome.
Propylthiouracil: Propylthiouracil Warnings: severe liver injury and acute liver failure, in some cases fatal, have been reported.
Protamine Sulfate: Protamine Sulfate Warnings: can cause severe hypotension, cardiovascular collapse, noncardiogenic pulmonary edema, catastrophic pulmonary vasoconstriction, and pulmonary hypertension.
Protriptyline: Protriptyline Warnings: suicidality and antidepressant drugs
Quazepam [Doral]: Quazepam [ Doral] Warnings: Risk From Concomitant Use With Opioids
Quetiapine [Seroquel – XR]: Quetiapine [Seroquel – XR] Warnings: increased mortality in elderly patients with dementia-related psychosis; and suicidal thoughts and behaviors
Quetiapine [Seroquel]: Quetiapine [Seroquel] Warnings: increased mortality in elderly patients with dementia-related psychosis; and suicidal thoughts and behaviors
Quinapril: Quinapril Warnings: fetal toxicity
Quinidine: Quinidine Warnings: mortality; proarrhythmic effects; paradoxical increase in ventricular rate in atrial flutter/fibrillation; exacerbated bradycardia in sick sinus syndrome; pharmacokinetic considerationsl vagolysis.
Quinine [Qualaquin]: Quinine [Qualaquin] Warnings: hematologic reactions
Raloxifene [Evista]: Raloxifene [Evista] Warnings: increased risk of venous thromboembolism and death from stroke
Ramipril: Ramipril Warnings: use in pregnancy – when used in pregnancy during the second and third trimesters, ace inhibitors can cause injury and even death to the developing fetus.
Ramucirumab [Cyramza]: Ramucirumab [Cyramza] Warnings: hemorrhage, gastrointestinal perforation, and impaired wound healing
Rasburicase [Elitek]: Rasburicase [Elitek] Warnings: ANAPHYLAXIS, HEMOLYSIS METHEMOGLOBINEMIA, AND INTERFERENCE WITH URIC ACID MEASUREMENTS
Regorafenib [Stivarga]: Regorafenib [Stivarga] Warnings: hepatotoxicity
Remifentanil: Remifentanil Addiction, Abuse, and Misuse
Reslizumab [Cinqair]: Reslizumab [Cinqair] Warnings: anaphylaxis
Ribavirin [Copegus]: Ribavirin [Copegus] Warnings: risk of serious disorders and ribavirin­-associated effects
Ribavirin [Rebetol]: Ribavirin [Rebetol] Warnings: risk of serious disorders and ribavirin­-associated effects
Ribavirin [Ribasphere]: Ribavirin [Ribasphere] Warnings: risk of serious disorders and ribavirin­-associated effects
Ribavirin [Virazole]: Ribavirin [Virazole] Use of aerosolized virazole in patients requiring mechanical ventilator assistance should be undertaken only by physicians and support staff familiar with the specific ventilator being used and this mode of administration of the drug.
Riociguat [Adempas]: Riociguat [Adempas] Warnings: embryo-fetal toxicity
Risperidone [Risperdal Consta]: Risperidone [Risperdal Consta] Warnings: increased mortality in elderly patients with dementia-related psychosis
Risperidone [Risperdal]: Risperidone [Risperdal] Warnings: increased mortality in elderly patients with dementia-related psychosis
Ritonavir [Norvir]: Ritonavir [Norvir] Warnings: drug-drug interactions leading to potentially serious and/or life threatening reactions
Rituximab [Rituxan]: Rituximab [Rituxan] Warnings: fatal infusion reactions, severe mucocutaneous reactions, hepatitis b virus reactivation and progressive multifocal leukoencephalopathy
Rivaroxaban [Xarelto]: Rivaroxaban [Xarelto] Warnings: (a) premature discontinuation of xarelto increases the risk of thrombotic events, (b) spinal/epidural hematoma
Rocuronium [Zemuron]: Rocuronium [Zemuron] Warnings: appropriate administration and monitoring; anaphylaxis; need for adequate anesthesia; residual paralysis; long-term use in an intensive care unit; malignant hyperthermia (mh); prolonged circulation time; qt interval prolongation; conditions/drugs causing potentiation of, or resistance to, neuromuscular block; incompatibility with alkaline solutions; increase in pulmonary vascular resistance; use in patients with myasthenial; extravasation.
Rosiglitazone [Avandia]: Rosiglitazone [Avandia] Warnings: congestive heart failure and myocardial ischemia
Rubidium Rb 82 [CardioGen-82]: Rubidium Rb 82 [CardioGen-82] Warnings: unintended strontium-82 (sr-82) and strontium-85 (sr-85) radiation exposure.
Sacubitril / Valsartan [Entresto]: Sacubitril / Valsartan [Entresto] Warnings: fetal toxicity
Salmeterol: Salmeterol Warnings: asthma-related death
Salmeterol [Serevent Diskus]: Serevent Diskus Warnings: ASTHMA-RELATED DEATH
Salsalate: Salsalate Warnings: cardiovascular risk
Saquinavir: warnings: risk of serious adverse reactions due to drug interactions; pr interval prolongation; qt interval prolongation; diabetes mellitus / hyperglycemia; hepatotoxicity; hemophilia; hyperlipidemia; lactose intolerance; fat redistribution;immune reconstitution syndrome; resistance/cross-resistance.
Sarilumab [Kevzara]: Sarilumab [Kevzara] Risk of serious infections
Selegiline: Selegiline Warnings: Selegiline should not be used at daily doses exceeding those recommended (10 mg/day) because of the risks associated with non-selective inhibition of MAO.
Selegiline [Emsam]: Selegiline [Emsam] Warnings: SUICIDAL THOUGHTS AND BEHAVIORS
Semaglutide [Ozempic]: Semaglutide [Ozempic] Warnings: RISK OF THYROID C-CELL TUMORS
Sertraline: Sertraline Warnings: suicidality and antidepressant drugs
Simeprevir [Olysio]: Simeprevir [Olysio] Warnings: risk of hepatitis b virus reactivation in patients coinfected with hcv and hbv
Sirolimus [Rapamune]: Sirolimus [Rapamune] Warnings: immunosuppression, use is not recommended in liver or lung transplant patients
Sodium Nitrite / Thiosulfuric acid [Nithiodote]: Sodium Nitrite / Thiosulfuric acid [Nithiodote] Warnings: LIFE THREATENING HYPOTENSION AND METHEMOGLOBIN FORMATION
Sodium Oxybate [Xyrem]: Sodium Oxybate [Xyrem] Warnings: central nervous system depression and misuse and abuse.
Sodium phosphate [Osmoprep]: Sodium phosphate [Osmoprep] Warnings: There have been rare, but serious reports of acute phosphate nephropathy in patients who received oral sodium phosphate products for colon cleansing prior to colonoscopy.
Sodium phosphate [Visicol]: Sodium phosphate [Visicol] There have been rare, but serious reports of acute phosphate nephropathy in patients who received oral sodium phosphate products for colon cleansing prior to colonoscopy.
Sofosbuvir / Velpatasvir / Voxilaprevir [Vosevi]: Sofosbuvir / Velpatasvir / Voxilaprevir [Vosevi] Risk of Hepatitis B Virus Reactivation in Patients Coinfected with HCV and HBV
Sofosbuvir / Velpatasvir [Epclusa]: Sofosbuvir / Velpatasvir [Epclusa] Warnings: risk of hepatitis b virus reactivation in patients coinfected with hcv and hbv
Sofosbuvir [Sovaldi]: Sofosbuvir [Sovaldi] Warnings: risk of hepatitis b virus reactivation in patients coinfected with hcv and hbv
Sonidegib [Odomzo]: Sonidegib [Odomzo] Warnings: embryo-fetal toxicity
Sotalol [Betapace]: Sotalol [Betapace] Warnings: LIFE THREATENING PROARRHYTHMIA
Sotalol [Sotylize]: Sotalol [Sotylize] Warnings: LIFE THREATENING PROARRHYTHMIA
Spironolactone [Aldactone]: Spironolactone [Aldactone] Warnings: tablets have been shown to be a tumorigen in chronic toxicity studies in rats. Should be used only in those conditions described under indications and usage. Unnecessary use of this drug should be avoided.
Stavudine [Zerit]: Stavudine [Zerit] Warnings: lactic acidosis and hepatomegaly with steatosis; pancreatitis
Streptomycin: Streptomycin Warnings: the risk of severe neurotoxic reactions is sharply increased in patients with impaired renal function or pre-renal azotemia.
Streptozocin [Zanosar]: Streptozocin [Zanosar] Warnings: should be administered under the supervision of a physician experienced in the use of cancer chemotherapeutic agents.
Succinylcholine [Anectine]: Succinylcholine [Anectine] Warnings: risk of cardiac arrest from hyperkalemic rhabdomyolysis
Succinylcholine [Quelicin]: Succinylcholine [Quelicin] Warnings: risk of cardiac arrest from hyperkalemic rhabdomyolysis
Sufentanil [Sufenta]: Sufentanil [Sufenta] Warnings: addiction, abuse, and misuse
Sulfur hexafluoride lipid-type A microspheres [Lumason]: Sulfur hexafluoride lipid-type A microspheres [Lumason] Warnings: SERIOUS CARDIOPULMONARY REACTIONS
Sulindac: Sulindac Warnings: cardiovascular thrombotic events; gastrointestinal risk
Sunitinib [Sutent]: Sunitinib [Sutent] Warnings: hepatotoxicity
Tacrolimus [Astagraf XL]: Tacrolimus [Astagraf XL] Warnings: malignancies and serious infections
Tacrolimus [Envarsus XR]: Tacrolimus [Envarsus XR] Warnings: malignancies and serious infections
Tacrolimus Injectable/Oral [Prograf]: Tacrolimus Injectable/Oral [Prograf] Warnings: malignancies and serious infections
Tacrolimus Ointment [Protopic] : Tacrolimus Ointment [Protopic] Warnings: Long-term safey of topical calcineurin inhibitors has not been established
Tamoxifen: Tamoxifen Warnings: for women with ductal carcinoma in situ (dcis) and women at high risk for breast cancer: serious and life-threatening events associated with tamoxifen in the risk reduction setting (women at high risk for cancer and women with dcis) include uterine malignancies, stroke and pulmonary embolism.
Tapentadol ER [Nucynta ER]: Tapentadol ER [Nucynta ER] Warnings: respiratory deptession; cns depression; head injury and increased intracranial pressure; msue and abuse;driving an operating machinery, interactions with alcohol and drus; seizures; serotonin syndorme risk; withdrawal; hepatic impairment; use in pancreatic/bilary tract disease.
Telaprevir [Incivek]: Telaprevir [Incivek] Warnings: SERIOUS SKIN REACTIONS
Telavancin [Vibativ]: Telavancin [Vibativ] Warnings: increased mortality in habp/vabp patients with pre-existing moderate or severe renal impairment, nephrotoxicity, potential adverse developmental outcomes
Telbivudine [Tyzeka]: Telbivudine [Tyzeka] Warnings: lactic acidosis/severe hepatomegaly with steatosis and severe acute exacerbations of hepatitis b
Telithromycin [Ketek]: Telithromycin [Ketek] Warnings: contraindicated in patients with myasthenia gravis.
Telmisartan: Warnings: fetal toxicity
Temazepam [Restoril]: Temazepam [Restoril] Risk From Concomitant Use With Opioids
Teniposide [Vumon]: Teniposide [Vumon] Warnings: teniposide is a potent drug and should be used only by physicians experienced in the administration of cancer chemotherapeutic drugs.
Tenofovir Alafenamide [Vemlidy]: Tenofovir Alafenamide [Vemlidy] Warnings: post treatment acute exacerbation of hepatitis b
Tenofovir Disoproxil Fumarate [Viread]: Tenofovir Disoproxil Fumarate [Viread] Warnings: Warnings: POSTTREATMENT EXACERBATION OF HEPATITIS
Terbutaline: Terbutaline Warnings: prolonged tocolysis
Teriflunomide [Aubagio]: Teriflunomide [Aubagio] Warnings: hepatotoxicity and risk of teratogenicity
Teriparatide [rDNA origin] Injection [Forteo]: Teriparatide [rDNA origin] Injection [Forteo] Warnings: potential risk of osteosarcoma
Testerosterone [Androgel 1%]: Testerosterone [Androgel 1%] Warnings: secondary exposure to testerosterone.
Testerosterone [Androgel 1.62%]: Testerosterone [Androgel 1.62%] Warnings: secondary exposure to testerosterone.
Testosterone [Fortesta]: Testosterone [Fortesta] Warnings: secondary exposure to testosterone
Testosterone [Testim]: Testosterone [Testim] Warnings: secondary exposure to testosterone
Testosterone [Vogelxo]: Testosterone [Vogelxo] Warnings: secondary exposure to testosterone
Testosterone Topical Solution [Axiron]: Testosterone Topical Solution [Axiron] Warnings: secondary exposure to testosterone
Testosterone Undecanoate Injection [Aveed]: Testosterone Undecanoate Injection [Aveed] Warnings: SERIOUS PULMONARY OIL MICROEMBOLISM (POME) REACTIONS AND ANAPHYLAXIS
Tetrabenazine [Xenazine]: Tetrabenazine [Xenazine] Warnings: depression and suicidality
Thalidomide [Thalomid]: Thalidomide [Thalomid] Warnings: embryo-fetal toxicity and venous thromboembolism
Thioridazine: Thioridazine Warnings: has been shown to prolong the qtc interval in a dose related manner, and drugs with this potential have been associated with torsades de pointes type arrhythmias and sudden death.
Thiotepa [Tepadina]: Thiotepa [Tepadina] Warnings: severe myelosuppression, carcinogenicity
Thiothixene: Thiothixene Warnings: increased mortality in elderly patients with dementia-related psychosis
Thrombin Alfa [Recothrom]: Thrombin Alfa [Recothrom] Warnings: severe bleeding and thrombosis complications; hypersensitivity reactions including anaphylaxis
Thrombin-JMI: Thrombin-JMI Warnings: severe bleeding and thrombosis complications
Thyroid, porcine: Thyroid, porcine Warnings: Drugs with thyroid hormone activity, alone or together with other therapeutic agents, have been used for the treatment of obesity. In euthyroid patients, doses within the range of daily hormonal requirements are ineffective for weight reduction. Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects.
Ticagrelor [Brilinta]: Ticagrelor [Brilinta] Warnings: (a) bleeding risk, (b) aspirin dose and brilinta effectiveness
Ticlopidine: Ticlopidine Warnings: can cause life-threatening hematological adverse reactions, including neutropenia/agranulocytosis, thrombotic thrombocytopenic purpura (ttp) and aplastic anemia.
Tigecycline [Tygacil]: Tigecycline [Tygacil] Warnings: all-cause mortality
Timolol: Timolol Warnings: as with other topically applied ophthalmic drugs, timolol ophthalmic solution is absorbed systemically. ;Cardiac failure; obstructive pulmonary disease; major surgery; diabetes mellitus; thyrotoxicosis.
Tinidazole [Tindamax]: Tinidazole [Tindamax] Warnings: potential risk for carcinogenicity
Tinzaparin: Tinzaparin Warnings: spinal/epidural hematomas
Tipranavir [Aptivus]: Tipranavir [Aptivus] Warnings: hepatotoxicity and intracranial hemorrhage
Tisagenlecleucel [Kymriah]: Tisagenlecleucel [Kymriah] Warnings: CYTOKINE RELEASE SYNDROME AND NEUROLOGICAL TOXICITIES .
Tizanidine [Zanaflex]: Tizanidine [Zanaflex] warnings: hypotension; risk of liver injury; sedation; hallucinosis/psychotic-like symptoms; interaction with cyp1a2 inhibitors; hypersensitivity reactions; increased risk of adverse reactions in patients with renal impairment; withdrawal adverse reactions.
Tobramycin: Tobramycin Warnings: patients treated with tobramycin injection and other aminoglycosides should be under close clinical observation, because these drugs have an inherent potential for causing ototoxicity and nephrotoxicity.
Tocilizumab [Actemra]: Tocilizumab [Actemra] Warnings: risk of serious infections
Tofacitinib [Xeljanz XR]: Tofacitinib [Xeljanz XR] Warnings: serious infections and malignancy
Tofacitinib [Xeljanz]: Tofacitinib [Xeljanz] Warnings: serious infections and malignancy
Tolcapone [Tasmar]: Tolcapone [Tasmar] Warnings: because of the risk of potentially fatal, acute fulminant liver failure, tolcapone should ordinarily be used in patients with parkinson’s disease on l-dopa/carbidopa who are experiencing symptom fluctuations and are not responding satisfactorily to or are not appropriate candidates for other adjunctive therapies.
Tolmetin: Tolmetin Warnings: cardiovascular risk; gastrointestinal risk
Tolvaptan [Samsca]: Tolvaptan [Samsca] Warnings: initiate and re-initiate in a hospital and monitor serum sodium
Topotecan [Hycamtin]: Topotecan [Hycamtin] Warnings: bone marrow suppression
Toremifene [Fareston]: Toremifene [Fareston] Warnings: qt prolongation
Tramadol [Conzip]: Tramadol [Conzip] Addiction , Abuse, and Misuse; Life-Threatening Respiratory Depression; Accidential Ingestion; Neonatal Opioid Withdrawal Syndrome; Interation with Drugs Affecting Cytochrome P450 Isoenzymes; and Risks From Concomitant Use With Benzodiazepines or Other CNS Depressants
Tramadol [Ultram ER]: Tramadol [Ultram ER] Addiction , Abuse, and Misuse; Life-Threatening Respiratory Depression; Accidential Ingestion; Neonatal Opioid Withdrawal Syndrome; Interation with Drugs Affecting Cytochrome P450 Isoenzymes; and Risks From Concomitant Use With Benzodiazepines or Other CNS Depressants
Tramadol [Ultram]: Tramadol [Ultram] Addiction , Abuse, and Misuse; Life-Threatening Respiratory Depression; Accidential Ingestion; Neonatal Opioid Withdrawal Syndrome; Interation with Drugs Affecting Cytochrome P450 Isoenzymes; and Risks From Concomitant Use With Benzodiazepines or Other CNS Depressants
Trandolapril [Mavik]: Trandolapril [Mavik] Warnings: fetal toxicity
Tranylcypromine: Tranylcypromine Warnings: suicidality and antidepressant drugs
Trastuzumab [Herceptin]: Trastuzumab [Herceptin] Warnings: hepatotoxicity, cardiac toxicity, embryo-fetal toxicity.
Trastuzumab-dkst [Ogivri]: Trastuzumab-dkst [Ogivri] Warnings: hepatotoxicity, cardiac toxicity, embryo-fetal toxicity.
Trazodone: Trazodone Warnings: suicidality and antidepressant drugs.
Tretinoin: Tretinoin Warnings: experienced physician and institution; retinoic acid-apl syndrome; leukocytosis at presentation and rapidly evolving leukocytosis during tretinoin capsules treatment; teratogenic effects. Pregnancy category d–see warnings..
Triamterene [Dyrenium]: Triamterene [Dyrenium] Warnings: Abnormal elevation of serum potassium levels (greater than or equal to 5.5 mEq/liter) can occur with all potassium-sparing agents.
Triazolam [Halcion]: Triazolam [Halcion] Risk From Concomitant Use With Opioids
Trifluoperazine: Trifluoperazine Warnings: increased mortality in elderly patients with dementia-related psychosis.
Trimipramine: Trimipramine Warnings: suicidality and antidepressant drugs.
Trovafloxacin: Trovafloxacin Warnings: has been associated with serious liver injury leading to liver transplantation and/or death.
Umeclidinium / Vilanterol [Anoro Ellipta]: Umeclidinium / Vilanterol [Anoro Ellipta] Warnings: ASTHMA-RELATED DEATH
Valaciclovir: Valaciclovir Warnings: hematologic toxicity, impairment of fertility, fetal toxicity, mutagenesis and carcinogenesis.
Valganciclovir [Valcyte]: Valganciclovir [Valcyte] Warnings: hematologic toxicity, impairment of fertility, fetal toxicity, mutagenesis and carcinogenesis.
Valporic Acid [Divalproex Sodium ]: Divalproex Sodium Warnings: life threatening adverse reactions
Valporic Acitd [Stavzor]: Valporic Acitd [Stavzor] Warnings: LIFE THREATENING ADVERSE REACTIONS
Valproate Sodium [Injection]: Valproate Sodium [Injection] Warnings: life threatening adverse reactions.
Valproic Acid [Depacon]: Valproic Acid [Depacon] Warnings: life threatening adverse reactions – hepatotoxicity; fetal risk; pancreatitis.
Valproic Acid [Depakene]: Valproic Acid [Depakene] Warnings: life threatening adverse reactions – hepatotoxicity; fetal risk; pancreatitis.
Valproic Acid [Depakote]: Valproic Acid [Depakote] Warnings: life threatening adverse reactions – hepatotoxicity; fetal risk; pancreatitis.
Valsartan [Diovan]: Valsartan [Diovan] Warnings: fetal toxicity.
Valsartan [Prexxartan]: Valsartan [Prexxartan] Warnings: ace inhibitor pregnancy risk
Vandetanib [Caprelsa]: Vandetanib [Caprelsa] Warnings: qt prolongation, torsades de pointes, and sudden death.
Varenicline [Chantix]: Varenicline [Chantix] Warnings: neuropsychiatric adverse events including suicidality; seizures; interaction with alcohol; accidental injury; cardiovascular events; somnambulism; angioedema and hypersensitivity reactions; serious skin reactions; nausea..
Vecuronium: Vecuronium Warnings: THIS DRUG SHOULD BE ADMINISTERED BY ADEQUATELY TRAINED INDIVIDUALS FAMILIAR WITH ITS ACTIONS, CHARACTERISTICS, AND HAZARDS.
Venlafaxine: Venlafaxine Warnings: suicidality and antidepressant drugs .
Vestronidase alfa-vjbk [Mepsevii]: Vestronidase alfa-vjbk [Mepsevii] Warnings: ANAPHYLAXIS
Vigabatrin [Sabril]: Vigabatrin [Sabril] Warnings: permanent vision loss.
Vilazodone: Warnings: suicidal thoughts and behaviors.
Vilazodone [Viibryd]:
Vilazodone [Viibryd] Warnings: suicidal thoughts and behaviors.
Vinblastine:
Vinblastine Warnings: This preparation should be administered by individuals experienced in the administration of vinblastine sulfate.
Vincristine:
Vincristine Warnings: caution – this preparation should be administered by individuals experienced in the administration of vincristine sulfate injection, usp..
Vincristine Liposome [Marqibo]:
Vincristine Liposome [Marqibo] Warnings: For Intravenous Use Only – Fatal if Given by Other Routes..
Vinorelbine [Navelbine]:
Vinorelbine [Navelbine] Warnings: myelosuppression.
Vismodegib [Erivedge]:
Vismodegib [Erivedge] Warnings: embryo-fetal toxicity.
Vorapaxar [Zontivity]:
Vorapaxar [Zontivity] Warnings: bleeding risk.
Vortioxetine [Brintellix]:
Vortioxetine [Brintellix] Warnings: suicidal thoughts and behaviors.
Warfarin:
Warfarin Warnings: bleeding risk.
Warfarin [Coumadin]:
Warfarin [Coumadin] Warnings: bleeding risk
Zalcitabine [discontinued]: Zalcitabine [discontinued]
Ziconotide [Prialt]:
Ziconotide [Prialt] Warnings: neuropsychiatric adverse reactions.
Zidovudine [Retrovir]:
Zidovudine [Retrovir] Warnings: risk of hematological toxicity, myopathy, lactic acidosis and severe hepatomegaly with steatosis.
Ziprasidone:
target=”_blank”>Ziprasidone Warnings: increased mortality in elderly patients with dementia-related psychosis.