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Dementia

The Medication Appropriateness Tool for Comorbid Health conditions in Dementia (MATCH-D) criteria provides expert consensus guidance about medication use for people with dementia. Click here to view.

The following are the definitions of the three stages of dementia used in the MATCH-D study along with the consensus guidance.

Early-stage dementia:mild cognitive impairment with a preserved ability to self‐care and undertake activities of daily living.”

Mid-stage dementia:moderate cognitive impairment with physical function often preserved. People with mid‐stage dementia may be living with support in the community or a low‐care residential aged care setting.”

Late-stage dementia:severe cognitive impairment and declining function (inability to recognize loved ones, unable to ambulate independently, incontinent of urine or feces).”

Early-stage

  • continue annual influenza vaccines indefinitely

Mid-stage

  • continue annual influenza vaccines indefinitely
  • use less stringent targets for blood pressure
  • use less stringent targets for blood glucose
  • cease lipid-lowering medications
  • cease medications that have a longer potential time to benefit than the person’s likely prognosis

Late-stage

  • use less stringent targets for blood glucose
  • only use diuretics for symptomatic management of heart failure
  • cease anti-hypertensive agents
  • cease lipid-lowering medications
  • cease medications to manage osteoporosis
  • cease anti-platelet, anti-coagulants and anti-thrombotic agents
  • cease all medications that do not also provide tangible symptom relief
  • cease medications that have a longer potential time to benefit than the person’s likely prognosis