Guides

Resources on reducing the medication burden — including algorithms, guidelines, and patient handouts.

Allopurinol
Antihyperglycemics
Antipsychotics

*Bruyere Research Institute at deprescribing.org

**Primary Health Tasmania


    • Thompson W, Quay TA, Rojas-Fernandez C, Farrell B, Bjerre LM. Atypical antipsychotics for insomnia: a systematic review. Sleep Med, 2016;22:13–7.
Antihypertensive agents
Aspirin
Benzodiazepine Receptor Agonists (aka BZD, BDZ, BZs, BZRA)

Benzodiazepine receptor agonists (BZD, BDZ, BZs), sometimes called “benzos” are a class of drugs are commonly known as minor tranquilizers. Older adults are at an increased risk of both short- and long-term adverse effects.

    • 5-fold higher risk of memory and concentration problems.
    • 4-fold increased risk of daytime fatigue.
    • 2-fold increased risk of falls and fractures (hip, wrist).
    • 2-fold increased risk of having a motor vehicle accident.

Benzos are listed in the Beers List of inappropriate medications for older adults.

*Bruyere Research Institute at deprescribing.org

**Primary Health Tasmania

Biophosphonates
Cholinesterase Inhibitors (ChEIs) and Memantine
First-generation antihistamines
Glaucoma eye drops
Non-steroidal anti-inflammatory drugs (NSAID)
Opioids
Proton Pump Inhibitors

*Bruyere Research Institute at deprescribing.org

**Primary Health Tasmania


Thompson W, Hogel M, Li Y, Thavorn K, O’Donnell D, McCarthy L, Dolovich L Black C, Farrell B. Effect of a proton pump inhibitor deprescribing guideline on drug usage and costs in long-term care. JAMDA, 2016, in press, doi.org/10.1016/j.jamda.2016.04.020.

Boghossian TA, Rashid FJ, Welch V, Rojas-Fernandez C, Moayyedi P, Pottie K, Walsh K, Pizzola L, Thompson W, Farrell B. Deprescribing versus continuation of chronic proton pump inhibitor use in adults (protocol). Cochrane Database Syst Rev, 2015; Issue 11, article number CD011969.

Sedative-hypnotic medications
Statins
Vitamin D and calcium