The information below is intended as a reference only, and should not be taken as medical advice. If you have questions about your medications, consult your pharmacist, doctor, nurse, or other healthcare professional.
If used daily for more than 3-4 weeks
- Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug.
- If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose.
Withdrawal Symptoms and monitoring guidance
If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose.
Anticholinergic drugs have traditionally been linked to cholinergic rebound syndrome that features jitteriness, nervousness, nausea, dizziness, insomnia, and nightmares. This has traditionally been thought to be a 48-72 hour problem.