The information below is intended as a reference only, and should not be taken as medical advice. If you have questions about your medications, consult your pharmacist, doctor, nurse, or other healthcare professional.
The Deprescribing Guidelines for the Elderly project has developed an evidence-based guideline to support clinicians in safely reducing or stopping proton pump inhibitors, a class of drugs that reduce acid production in the stomach. The team has also developed a deprescribing algorithm to help clinicians decide when and how to reduce proton pump inhibitors safely and how to monitor effect. See the resources below.
Bruyere Research Institute
- Proton Pump Inhibitor evidence-based deprescribing guideline
- Proton Pump Inhibitor deprescribing algorithm [PDF]
- Whiteboard video on using the Proton Pump Inhibitor deprescribing algorithm (YouTube)
- Patient handout on Proton Pump Inhibitors [PDF]
- Proton Pump Inhibitor (PPI) Patient Decision Aid [PDF]
Primary Health Tasmania
NSW Therapeutic Advisory Group Inc.
- Thompson W, Hogel M, Li Y, Thavorn K, O’Donnell D, McCarthy L, Dolovich L Black C, Farrell B. Effect of a proton pump inhibitor deprescribing guideline on drug usage and costs in long-term care. JAMDA, 2016, in press, doi.org/10.1016/j.jamda.2016.04.020.
- Boghossian TA, Rashid FJ, Welch V, Rojas-Fernandez C, Moayyedi P, Pottie K, Walsh K, Pizzola L, Thompson W, Farrell B. Deprescribing versus continuation of chronic proton pump inhibitor use in adults (protocol). Cochrane Database Syst Rev, 2015; Issue 11, article number CD011969.