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Pause and Monitor: Approach to reducing medication burden of polypharmacy

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Anticholinergic Deprescribing Resources

Resources

NSW Therapeutic Advisory Group Inc.

  • Neurological Drugs – Anticholinergic drugs for Parkinsonism [PDF]
  • Genitourinary Drugs – Anticholinergic drugs for Urinary Incontinence (Antimuscarinics) [PDF]

References & Relevant Literature

  1. Boustani MA, Campbell NL, Munger S, Maidment I, Fox GC. Impact of anticholinergics on the aging brain: a review and practical application. Aging Health. 2008;4(3):311-20.
  2. Richardson Kathryn, Fox Chris, Maidment Ian, Steel Nicholas, Loke Yoon K, Arthur Antony et al. Anticholinergic drugs and risk of dementia: case-control study BMJ 2018.
  3. Common anticholinergic drugs like Benadryl linked to increased dementia risk. Harvard Health Publishing.
  4. Patient Handout First-generation antihistamines. Bruyere Research Institute at deprescribing.org.
  5. Jama: Anticholinergic Drug Exposure and the Risk of Dementia A Nested Case-Control Study.
  6. Simon FER and Simons KJ. (2008). H1 Antihistamines. Current Status and Future Direction. Review article. World Allergy Organ J. 1(9): 145-155.
  7. Slavin RG. (2009). Treating rhinitis in the older population: special considerations. Allergy, Asthma, and Clin Immunol. Review. 5(1):9.
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